Table 1. Net Iron Balance in Cebus... | American Society of Hematology

Table 1.

Net Iron Balance in CebusMonkeys

	Dosage	Route	Vehicle	Predrug (μg/kg)	Postdrug (μg/kg)	Significance of t-test
DFO	150 μmol/kg	SC	dH₂O	169 ± 132	−278 ± 185	P < .001
HBED	75 μmol/kg	SC	40% Cremophor	173 ± 7	−606 ± 406	P < .005
HBED	150 μmol/kg	SC	40% Cremophor	175 ± 70	−1,141 ± 456	P < .001
HBED	150 μmol/kg	SC	buffer	212 ± 105	−689 ± 158	P < .001

	Dosage	Route	Vehicle	Predrug (μg/kg)	Postdrug (μg/kg)	Significance of t-test
DFO	150 μmol/kg	SC	dH₂O	169 ± 132	−278 ± 185	P < .001
HBED	75 μmol/kg	SC	40% Cremophor	173 ± 7	−606 ± 406	P < .005
HBED	150 μmol/kg	SC	40% Cremophor	175 ± 70	−1,141 ± 456	P < .001
HBED	150 μmol/kg	SC	buffer	212 ± 105	−689 ± 158	P < .001

The amount of iron absorbed by the untreated animals over a 3-day period is compared with the amount of iron excreted by the treated animals over a 3-day period. Net iron balance = dietary iron intake − (urinary iron + fecal iron). Animals in a negative iron balance are excreting more iron than they are absorbing.

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