Growth of 32Dcl3 Cells Expressing Wild-Type or ▵SH3 BCR/ABL in Hematopoietic Organs of SCID Mice
| Organs . | Wild-Type . | ΔSH3 . |
|---|---|---|
| Bone marrow | 44.9 ± 10.6 | 7.4 ± 4.5 |
| Spleen | 38.7 ± 3.8 | 7.3 ± 5.2 |
| Organs . | Wild-Type . | ΔSH3 . |
|---|---|---|
| Bone marrow | 44.9 ± 10.6 | 7.4 ± 4.5 |
| Spleen | 38.7 ± 3.8 | 7.3 ± 5.2 |
C.B-17/IcrTac-scid mice were injected intravenously with 5 × 106 32Dcl3 cells expressing the indicated BCR/ABL proteins. After 3 weeks, BMC and splenocytes were harvested and labeled with FITC-conjugated anti–H-2Kk antibody. Results are expressed as the percentage of positive cells (mean ± SD, 3 mice/group), as determined by flow cytometry.