Frequency of Solid Tumors Observed in Mice Injected With 164T2 and 267T2 Cells
| No. of Injected Cells . | Mice Injected With . | |
|---|---|---|
| 164T2 Cells . | 267T2 Cells . | |
| 1 × 105 | 17/32 | 0/20 |
| 5 × 105 | 5/5 | 0/5 |
| 1 × 106 | 10/10 | 0/10 |
| No. of Injected Cells . | Mice Injected With . | |
|---|---|---|
| 164T2 Cells . | 267T2 Cells . | |
| 1 × 105 | 17/32 | 0/20 |
| 5 × 105 | 5/5 | 0/5 |
| 1 × 106 | 10/10 | 0/10 |
Mice were considered positive if at least one solid tumor was found, either in the kidney, spleen, or liver. In most of the mice examined, tumor development of lymphoid tumors in kidneys was generally accompanied with severe splenomegaly. Development of lymphoma in kidneys was in all cases symmetrical. Tumor growth in all organs was confirmed by histologic examination.