Table 5.

Characterization of Engraftment of Selected CD34+ Blood Cells in BM of NOD/SCID Mice

Patient Engraftment (%)BCR-ABL+ Cells by FISH (%)*Phenotype CFU-GM/ 105 Cells
CD34 CD33 CD3 CD19
01  63  64  11  88 0  7  108  
01  54  35  15  71  0  20 104  
11  33  23  4  82  0  ND 
Patient Engraftment (%)BCR-ABL+ Cells by FISH (%)*Phenotype CFU-GM/ 105 Cells
CD34 CD33 CD3 CD19
01  63  64  11  88 0  7  108  
01  54  35  15  71  0  20 104  
11  33  23  4  82  0  ND 

Abbreviation: ND, not determined.

F4-150

Refers to percentage of human cells that are BCR-ABL+.

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