Karyotypic Findings by Classical Cytogenetics and FISH
| Case . | Status at Time of Analysis . | Cytogenetic Data . | Karyotype Update After FISH Studies . |
|---|---|---|---|
| 1 | P | 46,XY,t(5;12)(q31;p12)[4]/46,XY[2] | 46,XY,t(5;12)(q31;p13) |
| 2 | P | 46,XY[10] | |
| R/11 | 46,XY,t(6;12)(p21;p13)[1]/46,idem, del(15)(q21q22)[6]/46,XY[3] | 46,XY,t(6;12;17)(p21;p13;q25) | |
| 3 | P | 46,XY,t(7;12)(p14;p13)[17]/46,XY[3] | 46,XY,t(7;12)(p15;p13) |
| 4 | P | 45,XY,t(7;12)(p14;p13),−13[30]/46,XY[1] | 45,XY,t(7;12)(p12;p13),−13 |
| 5 | P | 46,XY,inv(2)(p11q13),add(7)(q36),del(12)(p12p13), der(16)t(1;16)(q22;p13),add(21)(q22)[19]/46,XY[1] | 46,XY,inv(2)(p11q13),t(7;12)(q36;p13),der(16)t(1;16) (q22;p13),add(21)(q22) |
| 6 | P | 46,XX[10] | |
| R/22 | 46,X,add(X)(q13),del(2)(p23),add(3)(p13),−9, del(12)(p12p13),der(12)t(9;12)(q13;p1?)t(13;20) (q14;p11),del(17)(p11),+mar[14]/46,XX[1] | 46,X,add(X)(q13),del(2)(p23),add(3)(p13),der(9)t(9;20) (q13;p12),del(12)(p12p13),der(12)t(12;13;9) (p13;q12q14;p13),der(13)t(12;13)(p13;q12), der(20)t(13;20)(q14;p12),del(17)(p11) | |
| 7 | P | 48,XY,der(1)add(1)(p34)add(1)(q21),der(7)t(1;7) (q21;q31),del(12)(p11),dic(12;17)(p11;p11), add(14)(q32),add(17)(p13),−19,−20,−22, +2-5mar[11]/96,idem[2]/46,XY[5] | 48,XY,der(1)t(1;17)(p34;q24)add(1)(q21),der(5) t(5;12;?)(p11;p11p13;?),der(7)t(1;7) (q21;q31),der(12)del(12)(p13p13)t(12;14) (p11;q32),dic(12;17)(p11;p11)del(12)(p13p13), del(14)(q32),der(14)t(12;14)(p11;q32),der(17)t(1;17) (p34;q24),der(17)t(12;17)(p13;q11),−19,−20,−22,+5mar |
| Case . | Status at Time of Analysis . | Cytogenetic Data . | Karyotype Update After FISH Studies . |
|---|---|---|---|
| 1 | P | 46,XY,t(5;12)(q31;p12)[4]/46,XY[2] | 46,XY,t(5;12)(q31;p13) |
| 2 | P | 46,XY[10] | |
| R/11 | 46,XY,t(6;12)(p21;p13)[1]/46,idem, del(15)(q21q22)[6]/46,XY[3] | 46,XY,t(6;12;17)(p21;p13;q25) | |
| 3 | P | 46,XY,t(7;12)(p14;p13)[17]/46,XY[3] | 46,XY,t(7;12)(p15;p13) |
| 4 | P | 45,XY,t(7;12)(p14;p13),−13[30]/46,XY[1] | 45,XY,t(7;12)(p12;p13),−13 |
| 5 | P | 46,XY,inv(2)(p11q13),add(7)(q36),del(12)(p12p13), der(16)t(1;16)(q22;p13),add(21)(q22)[19]/46,XY[1] | 46,XY,inv(2)(p11q13),t(7;12)(q36;p13),der(16)t(1;16) (q22;p13),add(21)(q22) |
| 6 | P | 46,XX[10] | |
| R/22 | 46,X,add(X)(q13),del(2)(p23),add(3)(p13),−9, del(12)(p12p13),der(12)t(9;12)(q13;p1?)t(13;20) (q14;p11),del(17)(p11),+mar[14]/46,XX[1] | 46,X,add(X)(q13),del(2)(p23),add(3)(p13),der(9)t(9;20) (q13;p12),del(12)(p12p13),der(12)t(12;13;9) (p13;q12q14;p13),der(13)t(12;13)(p13;q12), der(20)t(13;20)(q14;p12),del(17)(p11) | |
| 7 | P | 48,XY,der(1)add(1)(p34)add(1)(q21),der(7)t(1;7) (q21;q31),del(12)(p11),dic(12;17)(p11;p11), add(14)(q32),add(17)(p13),−19,−20,−22, +2-5mar[11]/96,idem[2]/46,XY[5] | 48,XY,der(1)t(1;17)(p34;q24)add(1)(q21),der(5) t(5;12;?)(p11;p11p13;?),der(7)t(1;7) (q21;q31),der(12)del(12)(p13p13)t(12;14) (p11;q32),dic(12;17)(p11;p11)del(12)(p13p13), del(14)(q32),der(14)t(12;14)(p11;q32),der(17)t(1;17) (p34;q24),der(17)t(12;17)(p13;q11),−19,−20,−22,+5mar |
Abbreviations: P, primary diagnosis; R, relapse/months after diagnosis.