Characteristics of Patients With Anaplastic Large-Cell Lymphoma According to the Phenotype of Tumor Cells
Characteristic . | B . | T . | Null . | P . |
---|---|---|---|---|
No.* | 56 | 49 | 33 | |
Sex | ||||
M | 30 | 38 | 19 | |
F | 26 | 11 | 14 | .03 |
Age (yr) | ||||
≤60 | 36 | 41 | 23 | |
>60 | 20 | 8 | 10 | .08 |
Performance status† | ||||
0-1 | 41 | 36 | 21 | |
>1 | 14 | 11 | 12 | .4 |
B symptoms† | ||||
Absent | 28 | 24 | 13 | |
Present | 27 | 24 | 20 | .5 |
Mediastinal involvement | 26 | 12 | 13 | .07 |
Extranodal sites | ||||
Bone marrow | 7 | 7 | 6 | .7 |
Liver | 4 | 8 | 3 | .3 |
Spleen | 14 | 6 | 5 | .2 |
Central nervous system | 5 | 3 | 3 | .8 |
Skin | 3 | 13 | 5 | .01 |
Lung | 10 | 6 | 7 | .5 |
Gut | 3 | 3 | 3 | .8 |
Bone | 4 | 3 | 4 | .6 |
Waldeyer's ring | 5 | 2 | 4 | .8 |
No. of extranodal sites | ||||
0-1 site | 41 | 38 | 27 | |
>1 sites | 15 | 11 | 6 | .6 |
Ann Arbor stage | ||||
I-II | 20 | 27 | 10 | |
III-IV | 36 | 22 | 23 | .05 |
LDH level† | ||||
≤1 × normal | 19 | 32 | 13 | |
>1 × normal | 31 | 16 | 18 | .01 |
Albumin level* | ||||
≤30 g/L | 10 | 15 | 7 | |
>30 g/L | 43 | 33 | 25 | .3 |
International prognostic index31† | ||||
Low | 16 | 31 | 12 | |
Low-intermediate | 16 | 4 | 6 | |
High-intermediate | 9 | 5 | 8 | |
High | 10 | 9 | 5 | .01 |
Treatment received | ||||
ACVBP | 28 | 20 | 17 | |
m-BACOD | 6 | 13 | 2 | |
NCVBP | 7 | 7 | 6 | |
VIM3/ACVBP | 8 | 6 | 3 | |
CVP/CTVP | 7 | 3 | 5 | .3 |
Characteristic . | B . | T . | Null . | P . |
---|---|---|---|---|
No.* | 56 | 49 | 33 | |
Sex | ||||
M | 30 | 38 | 19 | |
F | 26 | 11 | 14 | .03 |
Age (yr) | ||||
≤60 | 36 | 41 | 23 | |
>60 | 20 | 8 | 10 | .08 |
Performance status† | ||||
0-1 | 41 | 36 | 21 | |
>1 | 14 | 11 | 12 | .4 |
B symptoms† | ||||
Absent | 28 | 24 | 13 | |
Present | 27 | 24 | 20 | .5 |
Mediastinal involvement | 26 | 12 | 13 | .07 |
Extranodal sites | ||||
Bone marrow | 7 | 7 | 6 | .7 |
Liver | 4 | 8 | 3 | .3 |
Spleen | 14 | 6 | 5 | .2 |
Central nervous system | 5 | 3 | 3 | .8 |
Skin | 3 | 13 | 5 | .01 |
Lung | 10 | 6 | 7 | .5 |
Gut | 3 | 3 | 3 | .8 |
Bone | 4 | 3 | 4 | .6 |
Waldeyer's ring | 5 | 2 | 4 | .8 |
No. of extranodal sites | ||||
0-1 site | 41 | 38 | 27 | |
>1 sites | 15 | 11 | 6 | .6 |
Ann Arbor stage | ||||
I-II | 20 | 27 | 10 | |
III-IV | 36 | 22 | 23 | .05 |
LDH level† | ||||
≤1 × normal | 19 | 32 | 13 | |
>1 × normal | 31 | 16 | 18 | .01 |
Albumin level* | ||||
≤30 g/L | 10 | 15 | 7 | |
>30 g/L | 43 | 33 | 25 | .3 |
International prognostic index31† | ||||
Low | 16 | 31 | 12 | |
Low-intermediate | 16 | 4 | 6 | |
High-intermediate | 9 | 5 | 8 | |
High | 10 | 9 | 5 | .01 |
Treatment received | ||||
ACVBP | 28 | 20 | 17 | |
m-BACOD | 6 | 13 | 2 | |
NCVBP | 7 | 7 | 6 | |
VIM3/ACVBP | 8 | 6 | 3 | |
CVP/CTVP | 7 | 3 | 5 | .3 |