Main Features of 25 Patients With Mixed Cryoglobulinemia (MC)
| Case . | Age, Sex . | HLA B8/DR3 . | Cryo Type . | Liver Involvement-150 . | Peripheral Neuropathy . | Lymphoma . | Kidney Involvement . | Sicca Syndrome . |
|---|---|---|---|---|---|---|---|---|
| 1 | 62F | – | III | + | + | nd | – | – |
| 2 | 68F | – | II | + | + | nd | – | – |
| 3 | 65F | – | III | + | + | nd | – | – |
| 4 | 61F | – | III | + | – | nd | – | – |
| 5 | 64F | B8 | II | – | + | + | + | – |
| 6 | 60F | – | II | + | – | + | – | – |
| 7 | 49F | – | II | + | – | + | – | – |
| 8 | 67F | B8-DR3 | III | + | – | nd | – | – |
| 9 | 43F | B8-DR3 | II | + | – | nd | – | – |
| 10 | 55M | – | II | + | – | + | – | – |
| 11 | 54M | DR3 | III | + | – | + | – | – |
| 12 | 63F | B8 | II | + | – | + | + | – |
| 13 | 58F | – | III | + | – | nd | – | + |
| 14 | 75F | – | III | + | + | nd | – | – |
| 15 | 52F | B8-DR3 | II | – | + | + | – | – |
| 16 | 70F | B8-DR3 | III | – | + | + | – | + |
| 17 | 63F | – | III | + | + | nd | – | – |
| 18 | 50F | DR3 | II | + | + | nd | – | – |
| 19 | 57M | – | III | + | + | nd | – | – |
| 20 | 70F | B8-DR3 | II | + | + | nd | – | – |
| 21 | 50F | B8-DR3 | III | – | + | nd | – | – |
| 22 | 54F | – | II | + | + | nd | – | – |
| 23 | 44F | – | II | + | + | + | – | + |
| 24 | 72F | B8-DR3 | II | + | + | nd | + | – |
| 25 | 44F | B8-DR3 | II | + | – | nd | – | – |
| Case . | Age, Sex . | HLA B8/DR3 . | Cryo Type . | Liver Involvement-150 . | Peripheral Neuropathy . | Lymphoma . | Kidney Involvement . | Sicca Syndrome . |
|---|---|---|---|---|---|---|---|---|
| 1 | 62F | – | III | + | + | nd | – | – |
| 2 | 68F | – | II | + | + | nd | – | – |
| 3 | 65F | – | III | + | + | nd | – | – |
| 4 | 61F | – | III | + | – | nd | – | – |
| 5 | 64F | B8 | II | – | + | + | + | – |
| 6 | 60F | – | II | + | – | + | – | – |
| 7 | 49F | – | II | + | – | + | – | – |
| 8 | 67F | B8-DR3 | III | + | – | nd | – | – |
| 9 | 43F | B8-DR3 | II | + | – | nd | – | – |
| 10 | 55M | – | II | + | – | + | – | – |
| 11 | 54M | DR3 | III | + | – | + | – | – |
| 12 | 63F | B8 | II | + | – | + | + | – |
| 13 | 58F | – | III | + | – | nd | – | + |
| 14 | 75F | – | III | + | + | nd | – | – |
| 15 | 52F | B8-DR3 | II | – | + | + | – | – |
| 16 | 70F | B8-DR3 | III | – | + | + | – | + |
| 17 | 63F | – | III | + | + | nd | – | – |
| 18 | 50F | DR3 | II | + | + | nd | – | – |
| 19 | 57M | – | III | + | + | nd | – | – |
| 20 | 70F | B8-DR3 | II | + | + | nd | – | – |
| 21 | 50F | B8-DR3 | III | – | + | nd | – | – |
| 22 | 54F | – | II | + | + | nd | – | – |
| 23 | 44F | – | II | + | + | + | – | + |
| 24 | 72F | B8-DR3 | II | + | + | nd | + | – |
| 25 | 44F | B8-DR3 | II | + | – | nd | – | – |
Abbreviation: nd, not done.
Cirrhosis in 6 (no. 2, 14, 17, 22, 24, 25); chronic hepatitis in 11, abnormal ALT without biopsy in 4 (no. 4, 6, 10, 20).