Hematologic Values for F1 Wild-Type and Heterozygous Thalassemic Mice
| Genotype . | No. . | RBC (106/μL) . | Hb (g/dL) . | Hct (%) . | MCV (μm3) . | MCH (pg) . | MCHC (g/dL) . | RDW . |
|---|---|---|---|---|---|---|---|---|
| Hbb+/Hbb+ | 11 | 8.7 ± 0.3 | 15.0 ± 0.6 | 43.4 ± 1.9 | 49.5 ± 0.5 | 17.2 ± 0.1 | 34.8 ± 0.4 | 18.6 ± 2.5 |
| Hbbth-4/Hbb+ | 7 | 7.4 ± 0.4 | 11.7 ± 0.3 | 28.9 ± 0.8 | 39.7 ± 1.6 | 16.3 ± 1.1 | 40.7 ± 1.1 | 43.7 ± 0.6 |
| P | .01-150 | 4 × 10−4 -150 | 2 × 10−5 -150 | 3 × 10−6 -150 | .29 | 1 × 10−5 -150 | 8 × 10−7 -150 |
| Genotype . | No. . | RBC (106/μL) . | Hb (g/dL) . | Hct (%) . | MCV (μm3) . | MCH (pg) . | MCHC (g/dL) . | RDW . |
|---|---|---|---|---|---|---|---|---|
| Hbb+/Hbb+ | 11 | 8.7 ± 0.3 | 15.0 ± 0.6 | 43.4 ± 1.9 | 49.5 ± 0.5 | 17.2 ± 0.1 | 34.8 ± 0.4 | 18.6 ± 2.5 |
| Hbbth-4/Hbb+ | 7 | 7.4 ± 0.4 | 11.7 ± 0.3 | 28.9 ± 0.8 | 39.7 ± 1.6 | 16.3 ± 1.1 | 40.7 ± 1.1 | 43.7 ± 0.6 |
| P | .01-150 | 4 × 10−4 -150 | 2 × 10−5 -150 | 3 × 10−6 -150 | .29 | 1 × 10−5 -150 | 8 × 10−7 -150 |
Hematologic values are expressed as means ± SEM. Pvalues are for two-tailed Student's t tests in comparisons between Hbb+/Hbb+ andHbbth-4/Hbb+ mice assuming equal variance.
Abbreviations: RBC, red blood cells; Hb, hemoglobin; Hct, hematocrit; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; RDW, RBC distribution width.
Denotes significant P values.