RhD Epitopes Expressed by the DVI Types as Detected by Monoclonal Anti-D
| RhD Epitopes . | D Category VI . | Monoclonal Anti-D* Tested (n) . | ||
|---|---|---|---|---|
| Type I (n = 1) . | Type II (n = 1) . | Type III (n = 1) . | ||
| epD1 | Negative | Negative | Negative | 2 |
| epD2 | Negative | Negative | Negative | 2 |
| epD3 | Negative | Negative | Negative | 1 |
| epD4 | Negative | Negative | Negative | 1 |
| epD7 | Negative | Negative | Negative | 2 |
| epD10 | Negative | Negative | Negative | 7 |
| epD11 | Negative | Negative | Negative | 1 |
| epD12 | Negative | Negative | Negative | 6 |
| epD13 | Negative | Negative | Negative | 6 |
| epD15 | Negative | Negative | Negative | 9 |
| epD17 | Negative | Negative | Negative | 9 |
| epD18 | Negative | Negative | Negative | 8 |
| epD21 | Negative | Negative | Negative | 5 |
| epD22 | Negative | Negative | Negative | 2 |
| epD31 | Negative | Negative | Negative | 2 |
| epD32 | Negative | Negative | Negative | 1 |
| epD33 | Negative | Negative | Negative | 1 |
| epD34 | Negative | Negative | Negative | 1 |
| epD35 | Negative | Negative | Negative | 1 |
| epD5 | Positive | Positive | Positive | 5 |
| epD6 | Positive | Positive | Positive | 1 |
| epD23 | Positive | Positive | Positive | 8 |
| epD36 | Positive | Positive | Positive | 4 |
| epD37 | Positive | Positive | Positive | 4 |
| Reactivity With D Category VI Samples | Monoclonal Anti-D | |||
| Type I (n = 4) | Type II (n = 5) | Type III (n = 3) | ||
| epD3 | Negative | Variable† | Variable | LORE |
| epD15 | Negative | Variable | Variable | BIRMA-DG3 |
| epD15 | Negative | Variable | Variable | BTSN4 |
| epD15 | Variable | Variable | Variable | D90/7 |
| RhD Epitopes . | D Category VI . | Monoclonal Anti-D* Tested (n) . | ||
|---|---|---|---|---|
| Type I (n = 1) . | Type II (n = 1) . | Type III (n = 1) . | ||
| epD1 | Negative | Negative | Negative | 2 |
| epD2 | Negative | Negative | Negative | 2 |
| epD3 | Negative | Negative | Negative | 1 |
| epD4 | Negative | Negative | Negative | 1 |
| epD7 | Negative | Negative | Negative | 2 |
| epD10 | Negative | Negative | Negative | 7 |
| epD11 | Negative | Negative | Negative | 1 |
| epD12 | Negative | Negative | Negative | 6 |
| epD13 | Negative | Negative | Negative | 6 |
| epD15 | Negative | Negative | Negative | 9 |
| epD17 | Negative | Negative | Negative | 9 |
| epD18 | Negative | Negative | Negative | 8 |
| epD21 | Negative | Negative | Negative | 5 |
| epD22 | Negative | Negative | Negative | 2 |
| epD31 | Negative | Negative | Negative | 2 |
| epD32 | Negative | Negative | Negative | 1 |
| epD33 | Negative | Negative | Negative | 1 |
| epD34 | Negative | Negative | Negative | 1 |
| epD35 | Negative | Negative | Negative | 1 |
| epD5 | Positive | Positive | Positive | 5 |
| epD6 | Positive | Positive | Positive | 1 |
| epD23 | Positive | Positive | Positive | 8 |
| epD36 | Positive | Positive | Positive | 4 |
| epD37 | Positive | Positive | Positive | 4 |
| Reactivity With D Category VI Samples | Monoclonal Anti-D | |||
| Type I (n = 4) | Type II (n = 5) | Type III (n = 3) | ||
| epD3 | Negative | Variable† | Variable | LORE |
| epD15 | Negative | Variable | Variable | BIRMA-DG3 |
| epD15 | Negative | Variable | Variable | BTSN4 |
| epD15 | Variable | Variable | Variable | D90/7 |
*Clone identifications were listed in Materials and Methods as provided by Nantes Workshop.35 All monoclonal anti-D were tested with an identical random sample of each DVI type.
Reactivity with the monoclonal anti-Ds indicated on the left side was either weak positive or negative.