Table 4.

RhD Antigen Density of DVI Types

D Category VI RhD Antigen Densities (antigens per cell)*% of Reference3-152DVI Samples Tested (n)3-153
MedianMean3-151Range
Type I  502  489 204-1,169  3  5  
Type II  2,458  2,049 634-3,941  20  7  
Type III  13,294  12,699 11,018-13,981  106  
D Category VI RhD Antigen Densities (antigens per cell)*% of Reference3-152DVI Samples Tested (n)3-153
MedianMean3-151Range
Type I  502  489 204-1,169  3  5  
Type II  2,458  2,049 634-3,941  20  7  
Type III  13,294  12,699 11,018-13,981  106  

*The RhD antigen density of a sample was calculated as median of the epitopes per cell detected by the 22 IgG monoclonal anti-D.

F3-151

Geometric mean of the RhD antigen densities.

F3-152

Median RhD antigen density as percentage of control cells with comparable Rhesus phenotypes (CcDee 12,532 RhD antigens/cell; ccDEe 19,062).

F3-153

The RhD antigen densities of all three DVItypes were significantly different from one another (P < .007, t-test with correction for multiple testing (n = 3) according to Bonferroni-Holm).

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