Pyruvate Kinase Activity in RBCs of CBA-+/+ and-Pk-1slc/Pk-1slc Mice of Various Ages
Age of Mice (d) . | PK Activity (U/g hemoglobin)* . | |
---|---|---|
+/+ . | Pk-1slc/Pk-1slc . | |
1 | 159 ± 16 | 17 ± 2† |
7 | 76 ± 10 | 16 ± 3 |
14 | 40 ± 4‡ | 6.9 ± 0.6†,2-153 |
28 | 26 ± 2‡ | 3.8 ± 0.2†,2-153 |
42 | 21 ± 2‡ | 3.9 ± 0.1†,2-153 |
90 | 25 ± 1‡ | 4.1 ± 0.1†,2-153 |
Age of Mice (d) . | PK Activity (U/g hemoglobin)* . | |
---|---|---|
+/+ . | Pk-1slc/Pk-1slc . | |
1 | 159 ± 16 | 17 ± 2† |
7 | 76 ± 10 | 16 ± 3 |
14 | 40 ± 4‡ | 6.9 ± 0.6†,2-153 |
28 | 26 ± 2‡ | 3.8 ± 0.2†,2-153 |
42 | 21 ± 2‡ | 3.9 ± 0.1†,2-153 |
90 | 25 ± 1‡ | 4.1 ± 0.1†,2-153 |
*Mean ± SE of three samples; each sample was collected from various numbers of mice; for example, sample for day 1 from approximately 20 mice, sample for day 90 from 2 mice.
P < .01 when compared with values of CBA-+/+ mice of the same age by t-test.
P < .01 when compared with values of 1-day-old CBA-+/+ mice.
P < .01 when compared with values of 1-day-old CBA-Pk-1slc/Pk-1slc mice.