Table 3.

Pyruvate Kinase Activity in RBCs of CBA-+/+ and-Pk-1slc/Pk-1slc Mice of Various Ages

Age of Mice (d) PK Activity (U/g hemoglobin)*
+/+Pk-1slc/Pk-1slc
159 ± 16  17 ± 2 
7  76 ± 10  16 ± 3 
14  40 ± 4 6.9 ± 0.6,2-153 
28  26 ± 2 3.8 ± 0.2,2-153 
42  21 ± 2 3.9 ± 0.1,2-153 
90  25 ± 1 4.1 ± 0.1,2-153 
Age of Mice (d) PK Activity (U/g hemoglobin)*
+/+Pk-1slc/Pk-1slc
159 ± 16  17 ± 2 
7  76 ± 10  16 ± 3 
14  40 ± 4 6.9 ± 0.6,2-153 
28  26 ± 2 3.8 ± 0.2,2-153 
42  21 ± 2 3.9 ± 0.1,2-153 
90  25 ± 1 4.1 ± 0.1,2-153 

*Mean ± SE of three samples; each sample was collected from various numbers of mice; for example, sample for day 1 from approximately 20 mice, sample for day 90 from 2 mice.

P < .01 when compared with values of CBA-+/+ mice of the same age by t-test.

P < .01 when compared with values of 1-day-old CBA-+/+ mice.

F2-153

P < .01 when compared with values of 1-day-old CBA-Pk-1slc/Pk-1slc mice.

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