Table 4.

Patients With Low CsA-Sensitive Dye Efflux Are More Likely to Die Within the Next 12 Months Than Those With High CsA-Sensitive Dye Efflux

Patient StatusPatient Status of PBMC Samples in Which B Cells Have the Indicated % of CsA-Sensitive Dye Efflux
Less Than 35%Greater Than 35%
Exposed to VAD 6/13 (46%) 22/50 (44%) 
Exposed to M/P 5/13 (38%) 16/50 (32%) 
Other therapy 2/13 (15%) 6/50 (12%) 
Untreated 0/13 (<7%) 8/50 (16%) 
Samples taken within 12 mo of death4-150 6/13 (46%) 10/50 (20%) 
Total samples 13/63 (20%) 50/63 (80%) 
Patient StatusPatient Status of PBMC Samples in Which B Cells Have the Indicated % of CsA-Sensitive Dye Efflux
Less Than 35%Greater Than 35%
Exposed to VAD 6/13 (46%) 22/50 (44%) 
Exposed to M/P 5/13 (38%) 16/50 (32%) 
Other therapy 2/13 (15%) 6/50 (12%) 
Untreated 0/13 (<7%) 8/50 (16%) 
Samples taken within 12 mo of death4-150 6/13 (46%) 10/50 (20%) 
Total samples 13/63 (20%) 50/63 (80%) 

Patients listed as exposed to VAD received this treatment at some point in their therapy before the sample analyzed here; they may or may not also have received other types of therapy. Patients listed as exposed to M/P (melphalan/prednisone) received only M/P and had not been exposed to VAD.

F4-150

This group is comprised of the same patients listed in the preceding groups.

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