Viral Load in Lymphoma Tissue and Spleen Homogenate Based on Syncytia Induction on C8166 Human T Cells
| Monkey Code . | Tissue . | Grams* . | Volume of Homogenate (mL) . | TCID50/mL† . |
|---|---|---|---|---|
| 4 | Tumor mass | 0.65 | 2 | 1.0 × 105 |
| Spleen | 0.49 | 2 | 2.2 × 103 | |
| 8503 | Tumor mass | 0.73 | 2 | 1.7 × 104 |
| Spleen | 0.98 | 2.5 | 8.9 × 103 | |
| OD5 | Tumor mass | 1.25 | 2 | 3.1 × 103 |
| Spleen | ND‡ | |||
| 208 | Tumor mass | 0.51 | 2 | 3.1 × 103 |
| Spleen | 0.65 | 2 | 2.2 × 103 | |
| S1 | Tumor | 0.19 | 2 | 2.5 × 107 |
| Spleen | 0.80 | 2 | 3.1 × 103 |
| Monkey Code . | Tissue . | Grams* . | Volume of Homogenate (mL) . | TCID50/mL† . |
|---|---|---|---|---|
| 4 | Tumor mass | 0.65 | 2 | 1.0 × 105 |
| Spleen | 0.49 | 2 | 2.2 × 103 | |
| 8503 | Tumor mass | 0.73 | 2 | 1.7 × 104 |
| Spleen | 0.98 | 2.5 | 8.9 × 103 | |
| OD5 | Tumor mass | 1.25 | 2 | 3.1 × 103 |
| Spleen | ND‡ | |||
| 208 | Tumor mass | 0.51 | 2 | 3.1 × 103 |
| Spleen | 0.65 | 2 | 2.2 × 103 | |
| S1 | Tumor | 0.19 | 2 | 2.5 × 107 |
| Spleen | 0.80 | 2 | 3.1 × 103 |
*Grams are refereed to the weight of the tumor mass or the spleen homogenized.
TCID50 is defined by end-point dilution at which virus is able to infect 50% of cell cultures in an in vitro assay. The interpolation to obtain the tissue culture infectious dose 50% (TCID50) has been performed by the Reed and Muench method.
This monkey was splenectomized 1 year after infection.
Abbreviation: ND, not determined.