Table 4.

Clonogenic Cells After In Vitro Incubation of Ph-pos Cells With J-sp Antisense, J-nonsp Antisense, or Culture Medium at the Time of Diagnosis

Patients Untreated CellsCulture Medium Without ODN J-sp Antisense J-nonsp Antisense
ColoniesP Value3-150Colonies P Value3-151
1363-152 145  93  .002  100  NS  
90  94  20  .005  32  NS  
3  148 162  59  .001  66  NS  
4  142  116 42  .015  102  .034  
5  83  90  29  .001 42  NS  
6  140  135  20  .016  125 .015  
7  183  198  85  .006  126  NS 
8  136  124  13  .017  106  .028 
Patients Untreated CellsCulture Medium Without ODN J-sp Antisense J-nonsp Antisense
ColoniesP Value3-150Colonies P Value3-151
1363-152 145  93  .002  100  NS  
90  94  20  .005  32  NS  
3  148 162  59  .001  66  NS  
4  142  116 42  .015  102  .034  
5  83  90  29  .001 42  NS  
6  140  135  20  .016  125 .015  
7  183  198  85  .006  126  NS 
8  136  124  13  .017  106  .028 

Abbreviation: NS, not significant.

F3-150

Difference between the number of colonies grown after incubation of Ph-pos cells with the J-sp antisense ODN and culture medium without ODN.

F3-151

Difference between the number of colonies grown after incubation of Ph-pos cells with the J-nonsp antisense and the J-sp antisense ODN.

F3-152

Values are the mean of the number of colonies/105 cells grown in triplicate after 120 hours of incubation.

Close Modal

or Create an Account

Close Modal
Close Modal