Table 1. Effects of Hypoxia, Tiron, and... | American Society of Hematology

Table 1.

Effects of Hypoxia, Tiron, and Cobalt Chloride on the Binding of [¹²⁵I]-Prourokinase to HTR-8/SVneo Cells

Condition	B_max (sites/cell) ± SEM	kd (nmol/L) ± SEM	P (B_max)	P (kd)	No.
Standard versus hypoxia:
Standard	189,028 ± 39,222	1.26 ± 0.16			9
Hypoxia	356,728 ± 64,488	2.18 ± 0.42	.003	.025	9
Standard versus Tiron:
Standard	208,980 ± 26,825	2.93 ± 0.59			6
Tiron	623,213 ± 102,360	8.08 ± 1.11	.004	.001	6
Standard versus cobalt chloride:
Standard	223,026 ± 37,035	2.49 ± 0.47			8
Cobalt chloride	285,711 ± 38,324	3.58 ± 0.69	.014	.004	8

Condition	B_max (sites/cell) ± SEM	kd (nmol/L) ± SEM	P (B_max)	P (kd)	No.
Standard versus hypoxia:
Standard	189,028 ± 39,222	1.26 ± 0.16			9
Hypoxia	356,728 ± 64,488	2.18 ± 0.42	.003	.025	9
Standard versus Tiron:
Standard	208,980 ± 26,825	2.93 ± 0.59			6
Tiron	623,213 ± 102,360	8.08 ± 1.11	.004	.001	6
Standard versus cobalt chloride:
Standard	223,026 ± 37,035	2.49 ± 0.47			8
Cobalt chloride	285,711 ± 38,324	3.58 ± 0.69	.014	.004	8