Effects of Hypoxia, Carbon Monoxide, Tiron, and Cobalt Chloride on Invasion of HTR-8/SVneo Cells Through Matrigel
| Condition . | Invasion Index* (%) ± SE . | P (v standard) . | No. . |
|---|---|---|---|
| Standard (20% O2) | 100 | 11 | |
| Hypoxia (1% O2) | 141.4 ± 7.4 | .003 | 11 |
| Standard + cobalt chloride | 124.6 ± 8.4 | .028 | 9 |
| Standard + Tiron | 129.3 ± 12.7 | .035 | 6 |
| Hypoxia + 20% CO | 104.0 ± 8.5 | .684 | 10 |
| Condition . | Invasion Index* (%) ± SE . | P (v standard) . | No. . |
|---|---|---|---|
| Standard (20% O2) | 100 | 11 | |
| Hypoxia (1% O2) | 141.4 ± 7.4 | .003 | 11 |
| Standard + cobalt chloride | 124.6 ± 8.4 | .028 | 9 |
| Standard + Tiron | 129.3 ± 12.7 | .035 | 6 |
| Hypoxia + 20% CO | 104.0 ± 8.5 | .684 | 10 |
*The invasion index was calculated as described in Graham et al.17