Table 3.

Predictive Value of BCL-6 Gene Mutations in PT-LPDs: Regression Versus Resolution Versus No Response

BCL-6Regression Resolution (surg + chemo) No ResponseTotal
All cases  
 Wild type  8  9  1  18 
 100%  53%  20%  60% 
 Mutant  0  8  4  12  
 0% 47%  80%  40%  
 Total (P = .008)  8  17  5  30  
 26% 57%  17%  100%  
 
Polymorphic cases  
 Wild type  5  4  0  9  
 100% 40%  0%  53%  
 Mutant  0  2  8  
 0%  60%  100% 47%  
 Total (P = .02)  5  10  17  
 29%  59%  12% 100% 
BCL-6Regression Resolution (surg + chemo) No ResponseTotal
All cases  
 Wild type  8  9  1  18 
 100%  53%  20%  60% 
 Mutant  0  8  4  12  
 0% 47%  80%  40%  
 Total (P = .008)  8  17  5  30  
 26% 57%  17%  100%  
 
Polymorphic cases  
 Wild type  5  4  0  9  
 100% 40%  0%  53%  
 Mutant  0  2  8  
 0%  60%  100% 47%  
 Total (P = .02)  5  10  17  
 29%  59%  12% 100% 

Abbreviations: surg, surgery; chemo, chemotherapy.

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