Preparative Regimens Used in Patients With Advanced and Nonadvanced Disease
| Preparative Regimens . | Tacrolimus n (%) . | Cyclosporine n (%) . | P Values* . |
|---|---|---|---|
| Nonadvanced disease | 97 (100) | 116 (100) | .90 |
| Cyclophosphamide + TBI | 20 (21) | 19 (16) | |
| Cyclophosphamide + TBI + ara-C | 7 (7) | 6 (5) | |
| Cyclophosphamide + TBI + VP-16 | 7 (7) | 12 (10) | |
| TBI + VP-16 | 8 (8) | 9 (8) | |
| Busulfan + cyclophosphamide | 29 (30) | 33 (28) | |
| Busulfan + cyclophosphamide + ara-C | 20 (21) | 26 (22) | |
| Busulfan + cyclophosphamide + VP-16 | 2 (2) | 5 (4) | |
| Busulfan + cyclophosphamide + Thio-TEPA | 2 (2) | 5 (4) | |
| Other regimens | 2 (2) | 1 (1) | |
| Advanced disease | 68 (100) | 48 (100) | 1.0 |
| Cyclophosphamide + TBI | 8 (12) | 7 (15) | |
| Cyclophosphamide + TBI + ara-C | 7 (10) | 6 (12) | |
| Cyclophosphamide + TBI + VP-16 | 10 (15) | 7 (15) | |
| TBI + VP-16 | 3 (4) | 1 (2) | |
| Busulfan + cyclophosphamide | 9 (13) | 6 (12) | |
| Busulfan + cyclophosphamide + ara-C | 3 (4) | 2 (4) | |
| Busulfan + cyclophosphamide + VP-16 | 5 (7) | 5 (10) | |
| Busulfan + cyclophosphamide + Thio-TEPA | 11 (16) | 8 (17) | |
| Other regimens | 12 (18) | 6 (12) |
| Preparative Regimens . | Tacrolimus n (%) . | Cyclosporine n (%) . | P Values* . |
|---|---|---|---|
| Nonadvanced disease | 97 (100) | 116 (100) | .90 |
| Cyclophosphamide + TBI | 20 (21) | 19 (16) | |
| Cyclophosphamide + TBI + ara-C | 7 (7) | 6 (5) | |
| Cyclophosphamide + TBI + VP-16 | 7 (7) | 12 (10) | |
| TBI + VP-16 | 8 (8) | 9 (8) | |
| Busulfan + cyclophosphamide | 29 (30) | 33 (28) | |
| Busulfan + cyclophosphamide + ara-C | 20 (21) | 26 (22) | |
| Busulfan + cyclophosphamide + VP-16 | 2 (2) | 5 (4) | |
| Busulfan + cyclophosphamide + Thio-TEPA | 2 (2) | 5 (4) | |
| Other regimens | 2 (2) | 1 (1) | |
| Advanced disease | 68 (100) | 48 (100) | 1.0 |
| Cyclophosphamide + TBI | 8 (12) | 7 (15) | |
| Cyclophosphamide + TBI + ara-C | 7 (10) | 6 (12) | |
| Cyclophosphamide + TBI + VP-16 | 10 (15) | 7 (15) | |
| TBI + VP-16 | 3 (4) | 1 (2) | |
| Busulfan + cyclophosphamide | 9 (13) | 6 (12) | |
| Busulfan + cyclophosphamide + ara-C | 3 (4) | 2 (4) | |
| Busulfan + cyclophosphamide + VP-16 | 5 (7) | 5 (10) | |
| Busulfan + cyclophosphamide + Thio-TEPA | 11 (16) | 8 (17) | |
| Other regimens | 12 (18) | 6 (12) |
Abbreviations: TBI, total body irradiation; ara-C,cytosine arabinoside.
By Fisher's exact test.