Quantitative Data for EPAS-1 mRNA and HIF-1α mRNA Expression in a Range of Cell Lines
| Cell Line . | Tissue Origin . | EPAS-1 . | HIF-1α . | EPAS-1: HIF-1α . |
|---|---|---|---|---|
| RPMI 1788 | EBV lymphocyte | 4.4 | 13 | 0.34 |
| 293 | Embryonic kidney | 5.7 | 7.1 | 0.81 |
| HT29 | Colonic adenocarcinoma | 11 | 13 | 0.84 |
| HeLa (A) | Cervical carcinoma | 38 | 38 | 1.0 |
| HT1080 | Fibrosarcoma | 48 | 83 | 0.57 |
| HepG2 | Hepatoma | 90 | 39 | 2.3 |
| HeLa (B) | Cervical carcinoma | 99 | 25 | 3.9 |
| Hep3B | Hepatoma | 100 | 10 | 9.8 |
| BeWo | Choriocarcinoma | 242 | 26 | 9.4 |
| HMEC-1 | Microvascular endothelium | 952 | 46 | 21 |
| MRC5 | Foetal lung fibroblast | 1,284 | 133 | 9.6 |
| Cell Line . | Tissue Origin . | EPAS-1 . | HIF-1α . | EPAS-1: HIF-1α . |
|---|---|---|---|---|
| RPMI 1788 | EBV lymphocyte | 4.4 | 13 | 0.34 |
| 293 | Embryonic kidney | 5.7 | 7.1 | 0.81 |
| HT29 | Colonic adenocarcinoma | 11 | 13 | 0.84 |
| HeLa (A) | Cervical carcinoma | 38 | 38 | 1.0 |
| HT1080 | Fibrosarcoma | 48 | 83 | 0.57 |
| HepG2 | Hepatoma | 90 | 39 | 2.3 |
| HeLa (B) | Cervical carcinoma | 99 | 25 | 3.9 |
| Hep3B | Hepatoma | 100 | 10 | 9.8 |
| BeWo | Choriocarcinoma | 242 | 26 | 9.4 |
| HMEC-1 | Microvascular endothelium | 952 | 46 | 21 |
| MRC5 | Foetal lung fibroblast | 1,284 | 133 | 9.6 |
Expression is given relative to the level of EPAS-1 mRNA in Hep3B cells (100 arbitrary units).