Expression of MHC Class I and TAP-1 by HRS Cells in HD Specimens: Correlation With the Presence of EBV Within HRS Cells as Determined by EBER In Situ Hybridization (EBERs) and Subtype
| Specimen No. . | Subtype . | EBER . | MHC Class I . | TAP-1 . |
|---|---|---|---|---|
| 6828 | MC | + | + | + |
| 2491/86 | MC | + | + | + |
| 116/80 | MC | + | wk+ | wk+ |
| 2887/85 | MC | + | + | + |
| 8040/81 | MC | + | + | + |
| 444/85 | MC | + | − | + |
| 976B5/86 | MC | + | + | + |
| 3687-1/88 | MC | + | + | + |
| 18331/84 | MC | + | + | + |
| E7926/89 | MC | + | + | + |
| 5512/89 | NS | + | + | + |
| 1143/91 | NS | + | + | + |
| 9535/90 | NS | + | wk+ | wk+ |
| 9083/81 | NS | + | nd | + |
| 963A/84 | NS | + | + | + |
| SAJ2891/89 | NS | + | − | + |
| 1090/90S | NS | + | − | + |
| 1119B5/94S | NS | + | − | + |
| 6696/87 | LP | − | − | + |
| 2160/81 | LP | − | − | + |
| 3513/80 | MC | − | ± | + |
| 83s/3610 | MC | − | wk+ | + |
| 2959S85 | MC | − | − | + |
| 1633A/81 | MC | − | − | + |
| 22300/83 | MC | − | + | + |
| 9598/91 | NS | − | ± | + |
| 663/80 | NS | − | − | − |
| 5165/83S | NS | − | wk+ | + |
| 7590-2/85 | NS | − | − | + |
| 2153/87S | NS | − | − | + |
| 6870/87S | NS | − | + | + |
| 1220/90 | NS | − | − | + |
| 214F/90 | NS | − | − | + |
| 77/90 | NS | − | − | + |
| 180B/93S | NS | − | − | − |
| 5758B/91 | NS | − | − | + |
| 388/91S | NS | − | − | + |
| 1307/84 | NS | − | − | + |
| Y1114B/89 | NS | − | − | + |
| Specimen No. . | Subtype . | EBER . | MHC Class I . | TAP-1 . |
|---|---|---|---|---|
| 6828 | MC | + | + | + |
| 2491/86 | MC | + | + | + |
| 116/80 | MC | + | wk+ | wk+ |
| 2887/85 | MC | + | + | + |
| 8040/81 | MC | + | + | + |
| 444/85 | MC | + | − | + |
| 976B5/86 | MC | + | + | + |
| 3687-1/88 | MC | + | + | + |
| 18331/84 | MC | + | + | + |
| E7926/89 | MC | + | + | + |
| 5512/89 | NS | + | + | + |
| 1143/91 | NS | + | + | + |
| 9535/90 | NS | + | wk+ | wk+ |
| 9083/81 | NS | + | nd | + |
| 963A/84 | NS | + | + | + |
| SAJ2891/89 | NS | + | − | + |
| 1090/90S | NS | + | − | + |
| 1119B5/94S | NS | + | − | + |
| 6696/87 | LP | − | − | + |
| 2160/81 | LP | − | − | + |
| 3513/80 | MC | − | ± | + |
| 83s/3610 | MC | − | wk+ | + |
| 2959S85 | MC | − | − | + |
| 1633A/81 | MC | − | − | + |
| 22300/83 | MC | − | + | + |
| 9598/91 | NS | − | ± | + |
| 663/80 | NS | − | − | − |
| 5165/83S | NS | − | wk+ | + |
| 7590-2/85 | NS | − | − | + |
| 2153/87S | NS | − | − | + |
| 6870/87S | NS | − | + | + |
| 1220/90 | NS | − | − | + |
| 214F/90 | NS | − | − | + |
| 77/90 | NS | − | − | + |
| 180B/93S | NS | − | − | − |
| 5758B/91 | NS | − | − | + |
| 388/91S | NS | − | − | + |
| 1307/84 | NS | − | − | + |
| Y1114B/89 | NS | − | − | + |
Abbreviations: MC, mixed cellularity, NS, nodular sclerosis; LP, lymphocyte predominant, wk+, staining of HRS cells was weak only; ±, staining of HRS cells was equivocal; nd, not done.