Production of ¹⁴C-CO₂ is expressed as μmol/10¹⁰ cells/hour at 37°C. Mean values ± SD of 2 of 18 separate experiments (n) as indicated. TPE and SPE were separated from synchronized P falciparum cultures as detailed in Materials and Methods 34 to 38 and 40 to 44 hours after inoculum, respectively. Parasitemia was 95% to 100% TPE or SPE. NPE were kept in culture and processed in the same way as parasitized E. MB, 135 μmol/L final, was used to maximally stimulate¹⁴C-CO₂ production. P = significance to the first column to the right; P→→ = significance to the second column to the right; P↓ = significance within the same column. Significance of differences was assessed by t-test for paired samples.