Table 1.

TAA expression in patients with AML (n = 116): correlation with clinical parameters

BCL2
CA9
HMMR
LAMR1
PRAME
PRTN3
TERT
WT1
No vs at least 1 TAA
Older than 60 y, P  NS   NS   NS   NS   NS   NS   NS   NS   <.001  
WBC count below 30 × 109/L, P  NS   NS   .027   .002   NS   NS   NS   NS   NS  
LDH above median, P  NS   NS   NS   NS   NS   NS   NS   NS   NS  
Secondary AML, P  NS   NS   NS   .047   .020   NS   NS   NS   NS  
Karyotype subgroups, P  NS   .004   NS   .044   .001   .001   NS   NS   NS  
    t(15;17)   NS   ↓   NS   =   ↑   ↑   NS   NS   NS  
    t(8;21)   NS   =   NS   ↑   ↑   ↑   NS   NS   NS  
    inv(16)   NS   =   NS   =   ↓   ↑   NS   NS   NS  
    t(9;11)   NS   ↑   NS   =   =   ↓   NS   NS   NS  
    Normal karyotype   NS   =   NS   ↓   ↓   ↓   NS   NS   NS  
    +8 sole   NS   =   NS   ↓   =   ↑   NS   NS   NS  
    -7/del(7q)   NS   ↑   NS   ↑   ↑   ↓   NS   NS   NS  
    Complex karyotype   NS   ↓   NS   =   ↓   ↓   NS   NS   NS  
    Others   NS   =   NS   ↑   ↓   ↓   NS   NS   NS  
FLT3 ITD, P  NS   NS   NS   NS   NS   NS   NS   .046   NS  
MLL PTD, P
 		 NS
 		 NS
 		 NS
 		 NS
 		 NS
 		 NS
 		 NS
 		 NS
 		 NS
 
BCL2
CA9
HMMR
LAMR1
PRAME
PRTN3
TERT
WT1
No vs at least 1 TAA
Older than 60 y, P  NS   NS   NS   NS   NS   NS   NS   NS   <.001  
WBC count below 30 × 109/L, P  NS   NS   .027   .002   NS   NS   NS   NS   NS  
LDH above median, P  NS   NS   NS   NS   NS   NS   NS   NS   NS  
Secondary AML, P  NS   NS   NS   .047   .020   NS   NS   NS   NS  
Karyotype subgroups, P  NS   .004   NS   .044   .001   .001   NS   NS   NS  
    t(15;17)   NS   ↓   NS   =   ↑   ↑   NS   NS   NS  
    t(8;21)   NS   =   NS   ↑   ↑   ↑   NS   NS   NS  
    inv(16)   NS   =   NS   =   ↓   ↑   NS   NS   NS  
    t(9;11)   NS   ↑   NS   =   =   ↓   NS   NS   NS  
    Normal karyotype   NS   =   NS   ↓   ↓   ↓   NS   NS   NS  
    +8 sole   NS   =   NS   ↓   =   ↑   NS   NS   NS  
    -7/del(7q)   NS   ↑   NS   ↑   ↑   ↓   NS   NS   NS  
    Complex karyotype   NS   ↓   NS   =   ↓   ↓   NS   NS   NS  
    Others   NS   =   NS   ↑   ↓   ↓   NS   NS   NS  
FLT3 ITD, P  NS   NS   NS   NS   NS   NS   NS   .046   NS  
MLL PTD, P
 		 NS
 		 NS
 		 NS
 		 NS
 		 NS
 		 NS
 		 NS
 		 NS
 		 NS
 

NS indicates not significant (P > .05); higher expression levels compared to the mean expression of the respective TAA; =, mean expression of the respective TAA; ↓, lower expression levels compared to the mean expression of the respective TAA; and PTD, partial tandem duplication.

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