Table 6.

Combined risk of myocardial infarction by tertiles of factor XIc and factor XIIc


FXIc/FXIIc

Patients

Control subjects

OR (95% CI)*

OR (95% CI)
FXIc less than 100%     
    FXIIc more than 109%   5   26   1  1 
    FXIIc 91%-109%   44   72   3.3 (1.2-9.3)   4.5 (0.5-38.9)  
    FXIIc less than 91%   82   110   4.1 (1.5-11.1)   7.4 (0.9-61.4)  
FXIc 100%-116%     
    FXIIc more than 109%   28   76   1.9 (0.7-5.4)   2.5 (0.3-22.5)  
    FXIIc 91%-109%   84   85   5.3 (1.9-14.6)   15.0 (1.8-122.0)  
    FXIIc less than 91%   114   62   9.9 (3.6-27.2)   17.6 (2.1-145.0)  
FXIc more than 116%     
    FXIIc more than 109%   80   111   3.7 (1.4-10.1)   7.4 (0.9-60.5)  
    FXIIc 91%-109%   69   59   6.1 (2.2-17.0)   5.6 (0.6-47.9)  
    FXIIc less than 91%
 
54
 
45
 
6.4 (2.2-18.0)
 
11.6 (1.4-98.5)
 

FXIc/FXIIc

Patients

Control subjects

OR (95% CI)*

OR (95% CI)
FXIc less than 100%     
    FXIIc more than 109%   5   26   1  1 
    FXIIc 91%-109%   44   72   3.3 (1.2-9.3)   4.5 (0.5-38.9)  
    FXIIc less than 91%   82   110   4.1 (1.5-11.1)   7.4 (0.9-61.4)  
FXIc 100%-116%     
    FXIIc more than 109%   28   76   1.9 (0.7-5.4)   2.5 (0.3-22.5)  
    FXIIc 91%-109%   84   85   5.3 (1.9-14.6)   15.0 (1.8-122.0)  
    FXIIc less than 91%   114   62   9.9 (3.6-27.2)   17.6 (2.1-145.0)  
FXIc more than 116%     
    FXIIc more than 109%   80   111   3.7 (1.4-10.1)   7.4 (0.9-60.5)  
    FXIIc 91%-109%   69   59   6.1 (2.2-17.0)   5.6 (0.6-47.9)  
    FXIIc less than 91%
 
54
 
45
 
6.4 (2.2-18.0)
 
11.6 (1.4-98.5)
 

For patients, N = 560; for control subjects, N = 646.

*

Adjusted for age.

Adjusted for age, total cholesterol, HDL-cholesterol, and triglyceride levels; quetelet index; smoking; alcohol use; and diabetes, excluding persons having hypertension.

Reference group.

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