Table 2 Obatoclax dose levels and cycles... | American Society of Hematology

Table 2

Obatoclax dose levels and cycles

Obatoclax dose, mg/m²	No. of patients	Median cycles	Cycle range	Dose escalations
1-hour infusion
3.5	2	3	3-6	1-10 mg/m²
5	1	2	2
7	2	2	2-3	1-10 mg/m²
10	3	4	4-7	3-14 mg/m²
14	4	2	1-4
3-hour infusion
20	3	2	2-5
28	7	2	1-7	1-40 mg/m²
40	4	2	1-2
Overall	26	2	1-7

Obatoclax dose, mg/m²	No. of patients	Median cycles	Cycle range	Dose escalations
1-hour infusion
3.5	2	3	3-6	1-10 mg/m²
5	1	2	2
7	2	2	2-3	1-10 mg/m²
10	3	4	4-7	3-14 mg/m²
14	4	2	1-4
3-hour infusion
20	3	2	2-5
28	7	2	1-7	1-40 mg/m²
40	4	2	1-2
Overall	26	2	1-7