Table 5

Multivariable prognostic analysis for DFS and risk of BM relapse (on 93 patients evaluable for all risk variables)

Risk factorNo. (%)DFS
BM relapse
Hazard ratioSE95% CIPHazard ratioSE95% CIP
MRDpos 44 (47.3) 5.88 2.16 2.86-12.08 .001 5.33 2.20 2.38-11.96 .001 
WBC more than 100 9 (9.7) 5.13 2.38 2.06-12.75 .001 4.32 2.25 1.56-11.99 .005 
WBC more than 30 24 (25.8) 2.57 0.88 1.32-5.02 .006 2.27 0.90 1.04-4.96 .040 
HR phenotype 16 (17.2) 1.68 0.64 0.79-3.55 .176 2.04 0.85 0.90-4.63 .085 
HR cytogenetics 23 (24.7) 1.04 0.38 0.52-2.12 .901 0.96 0.41 0.42-2.21 .934 
Age older than 55 y 15 (16.1) 1.36 0.67 0.52-3.59 .530 1.44 0.80 0.49-4.29 .508 
Risk factorNo. (%)DFS
BM relapse
Hazard ratioSE95% CIPHazard ratioSE95% CIP
MRDpos 44 (47.3) 5.88 2.16 2.86-12.08 .001 5.33 2.20 2.38-11.96 .001 
WBC more than 100 9 (9.7) 5.13 2.38 2.06-12.75 .001 4.32 2.25 1.56-11.99 .005 
WBC more than 30 24 (25.8) 2.57 0.88 1.32-5.02 .006 2.27 0.90 1.04-4.96 .040 
HR phenotype 16 (17.2) 1.68 0.64 0.79-3.55 .176 2.04 0.85 0.90-4.63 .085 
HR cytogenetics 23 (24.7) 1.04 0.38 0.52-2.12 .901 0.96 0.41 0.42-2.21 .934 
Age older than 55 y 15 (16.1) 1.36 0.67 0.52-3.59 .530 1.44 0.80 0.49-4.29 .508 

WBC indicates white blood cell (×109/L).

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