Table 2 Combination index values for... | American Society of Hematology

Table 2

Combination index values for effects of Nutlin-3 and γ-secretase inhibitor L-685,458 on cell viability

Sample	ED50	ED75	ED90	Average CI*
SKW6.4	0.22	0.35	0.76	0.44
OCI	0.74	0.60	0.48	0.61
Patient no. 1	0.73	1.31	2.36	1.47
Patient no. 2	0.42	0.81	1.59	0.94
Patient no. 3	0.52	0.50	0.54	0.52
Patient no. 6	0.35	0.38	0.52	0.42
Patient no. 7	0.24	0.38	0.62	0.30
Patient no. 8	0.56	0.63	0.84	0.68
Patient no. 9	0.64	0.82	1.05	0.84
Patient no. 11	0.40	0.93	1.61	0.98
Patient no. 13	0.21	0.45	0.96	0.54
Patient no. 14	0.56	0.46	0.38	0.47
Patient no. 17	0.41	0.47	0.53	0.47
Patient no. 18	0.70	0.75	0.95	0.80
Patient no. 22	0.37	0.23	0.17	0.26
Patient no. 23	0.24	0.38	0.62	0.41
Patient no. 24	0.26	0.80	0.51	0.86
Patient no. 26	0.52	0.60	0.70	0.61

Sample	ED50	ED75	ED90	Average CI*
SKW6.4	0.22	0.35	0.76	0.44
OCI	0.74	0.60	0.48	0.61
Patient no. 1	0.73	1.31	2.36	1.47
Patient no. 2	0.42	0.81	1.59	0.94
Patient no. 3	0.52	0.50	0.54	0.52
Patient no. 6	0.35	0.38	0.52	0.42
Patient no. 7	0.24	0.38	0.62	0.30
Patient no. 8	0.56	0.63	0.84	0.68
Patient no. 9	0.64	0.82	1.05	0.84
Patient no. 11	0.40	0.93	1.61	0.98
Patient no. 13	0.21	0.45	0.96	0.54
Patient no. 14	0.56	0.46	0.38	0.47
Patient no. 17	0.41	0.47	0.53	0.47
Patient no. 18	0.70	0.75	0.95	0.80
Patient no. 22	0.37	0.23	0.17	0.26
Patient no. 23	0.24	0.38	0.62	0.41
Patient no. 24	0.26	0.80	0.51	0.86
Patient no. 26	0.52	0.60	0.70	0.61

ED indicates effect dose.

The averaged combination index (CI) values were calculated from ED50, ED75, and ED90.