Iron parameters in B6 and D2 mice fed diets with different iron contents
| Diet . | Serum iron, μM . | TIBC, μM . | Transferrin saturation . | Liver iron concentration, μg iron/g dry weight . |
|---|---|---|---|---|
| B6 strain | ||||
| Iron deficient | 7.12 ± 1.90 | 61.12 ± 4.63 | 11 ± 3% | 211 ± 24 |
| Iron adequate | 11.28 ± 1.63 | 39.36 ± 1.98 | 29 ± 4% | 441 ± 85 |
| Iron supplemented | 30.46 ± 1.69 | 30.74 ± 0.94 | 99 ± 7% | 3569 ± 502 |
| D2 strain | ||||
| Iron deficient | 7.32 ± 1.31 | 66.78 ± 8.35 | 11 ± 3% | 224 ± 44 |
| Iron adequate | 22.18 ± 3.37 | 52.20 ± 3.66 | 42 ± 4% | 502 ± 69 |
| Iron supplemented | 31.38 ± 2.80 | 43.62 ± 3.97 | 72 ± 3% | 2353 ± 163 |
| Diet . | Serum iron, μM . | TIBC, μM . | Transferrin saturation . | Liver iron concentration, μg iron/g dry weight . |
|---|---|---|---|---|
| B6 strain | ||||
| Iron deficient | 7.12 ± 1.90 | 61.12 ± 4.63 | 11 ± 3% | 211 ± 24 |
| Iron adequate | 11.28 ± 1.63 | 39.36 ± 1.98 | 29 ± 4% | 441 ± 85 |
| Iron supplemented | 30.46 ± 1.69 | 30.74 ± 0.94 | 99 ± 7% | 3569 ± 502 |
| D2 strain | ||||
| Iron deficient | 7.32 ± 1.31 | 66.78 ± 8.35 | 11 ± 3% | 224 ± 44 |
| Iron adequate | 22.18 ± 3.37 | 52.20 ± 3.66 | 42 ± 4% | 502 ± 69 |
| Iron supplemented | 31.38 ± 2.80 | 43.62 ± 3.97 | 72 ± 3% | 2353 ± 163 |
Results are expressed as mean ± SD (n=5 mice per group). Analyses of variance show that, within each strain, the dietary iron content significantly affects serum iron, total iron binding capacity (TIBC), transferrin saturation, as well as hepatic iron concentration (all P values are < .001).