Table 2 Examples of copy neutral LOH and... | American Society of Hematology

Table 2

Examples of copy neutral LOH and corresponding gene mutations in homozygous form

Area of UPD	Gene	Disease	Reference
UPD9q	Jak2	MPD	Kralovics et al^37,38
UPD13q	FTL-ITD	AML	Raghavan et al³⁹
UPD17q	NF-1	JMML	Flotho⁴²
UPD21q	AML-1/Runx1	AML	Raghavan et al³⁹
UPD19q	CEBPA	AML	Raghavan et al³⁹; Fitzgibbon et al⁴¹
UPD4q	c-Kit	AML	Unpublished results*
UPD1p	c-Mpl	MDS/MPD, MPD	Unpublished results†
UPD11p	WT1	AML	Raghavan et al³⁹

Area of UPD	Gene	Disease	Reference
UPD9q	Jak2	MPD	Kralovics et al^37,38
UPD13q	FTL-ITD	AML	Raghavan et al³⁹
UPD17q	NF-1	JMML	Flotho⁴²
UPD21q	AML-1/Runx1	AML	Raghavan et al³⁹
UPD19q	CEBPA	AML	Raghavan et al³⁹; Fitzgibbon et al⁴¹
UPD4q	c-Kit	AML	Unpublished results*
UPD1p	c-Mpl	MDS/MPD, MPD	Unpublished results†
UPD11p	WT1	AML	Raghavan et al³⁹

A. Dunbar, L.P. Gondek, C.H. O'Keefe, M.A. McDevitt, J.P.M. (manuscript submitted March 2008).

H. Szpurka, February 2008.