Table 1 Consensus AML1 DNA-binding... | American Society of Hematology

Table 1

Consensus AML1 DNA-binding sites, TGCGGT (1) and TGTGGT (2), in the selected DNA sequences

	AML1 (A)	AML1-ETO (AE)	AML1-ETOtr (AEtr)	N-terminal AML1*
(1) × 1 time	20	9	7	13
(2) × 1 time	7	3	0	13
(1) × 2-3 times	14	25	33	0
(2) × 2-3 times	0	0	1	5
(1) and (2) mixed	14	17	9	1
No site	9	3	0	6
No. of total clones	64	57	50	38
1 site, %	49	22	14	81
2-3 sites,† %	51	78	86	19

	AML1 (A)	AML1-ETO (AE)	AML1-ETOtr (AEtr)	N-terminal AML1*
(1) × 1 time	20	9	7	13
(2) × 1 time	7	3	0	13
(1) × 2-3 times	14	25	33	0
(2) × 2-3 times	0	0	1	5
(1) and (2) mixed	14	17	9	1
No site	9	3	0	6
No. of total clones	64	57	50	38
1 site, %	49	22	14	81
2-3 sites,† %	51	78	86	19

The result of N-terminal AML1 is from Meyers et al.⁷

By Fisher exact test, the difference between AML1/N-terminal AML1 and AML1-ETO/ AML1-ETOtr is statistically significant (P = .001).