Recurrent VTE according to D-dimer time course from the third month
| Outcomes . | Normal D-d at T90* . | Abnormal D-d at T90† . | Abnormal D-d after T90‡ . |
|---|---|---|---|
| N (%, 95% CI) | 149 (66, 59-72) | 31 (14, 10-19) | 46 (20.3, 15-26) |
| n (%, 95% CI) | 4 (2.7, 1-7) | 7 (22.6, 10-41)§ | 5 (10.9, 4-24)∥ |
| n/100 person, y (95% CI) | 2.9 (1-7) | 27 (12-48) | 11.1 (4-24) |
| Patient years | 138 | 25.6 | 45 |
| Type of recurrent VTE¶ | |||
| DVT | 4 | 6 | 4 |
| DVT + PE | 0 | 0 | 0 |
| Isolated PE | 0 | 1 | 1 |
| Outcomes . | Normal D-d at T90* . | Abnormal D-d at T90† . | Abnormal D-d after T90‡ . |
|---|---|---|---|
| N (%, 95% CI) | 149 (66, 59-72) | 31 (14, 10-19) | 46 (20.3, 15-26) |
| n (%, 95% CI) | 4 (2.7, 1-7) | 7 (22.6, 10-41)§ | 5 (10.9, 4-24)∥ |
| n/100 person, y (95% CI) | 2.9 (1-7) | 27 (12-48) | 11.1 (4-24) |
| Patient years | 138 | 25.6 | 45 |
| Type of recurrent VTE¶ | |||
| DVT | 4 | 6 | 4 |
| DVT + PE | 0 | 0 | 0 |
| Isolated PE | 0 | 1 | 1 |
D-d indicates D-dimer; VTE, venous thromboembolism; DVT, deep vein thrombosis; and PE, pulmonary embolism.
D-d always normal from T90 but once in 25 patients.
D-d always abnormal from T90 in 14 patients and abnormal at least twice in 17 patients.
D-d always abnormal after T90 in 23 patients and abnormal at least twice in 23 patients.
P = .001 vs normal D-d.
P = .035 vs normal D-d.
Seven DVTs occurred in the ipsilateral limb and 7 in the contralateral limb, 1 event was distal DVT, all recurrent events were idiopathic except for 1 DVT secondary to trauma in a patient with normal D-d at T90.