Table 3

Gene ontology pathways overrepresented in the differential DS-ALL signature

Gene ontology groupSizePFDR, %
GO:0006974∼ response to DNA damage stimulus 16 < .001 0.77 
GO:0006397∼ mRNA processing 13 .002 2.80 
GO:0015031∼ protein transport 24 .002 3.30 
GO:0008104∼ protein localization 26 .002 3.70 
GO:0046907∼ intracellular transport 24 .003 4.40 
GO:0065003∼ macromolecular complex assembly 20 .004 5.80 
GO:0051649∼ establishment of cellular localization 27 .005 7.60 
GO:0043067∼ regulation of programmed cell death 19 .006 9.10 
Gene ontology groupSizePFDR, %
GO:0006974∼ response to DNA damage stimulus 16 < .001 0.77 
GO:0006397∼ mRNA processing 13 .002 2.80 
GO:0015031∼ protein transport 24 .002 3.30 
GO:0008104∼ protein localization 26 .002 3.70 
GO:0046907∼ intracellular transport 24 .003 4.40 
GO:0065003∼ macromolecular complex assembly 20 .004 5.80 
GO:0051649∼ establishment of cellular localization 27 .005 7.60 
GO:0043067∼ regulation of programmed cell death 19 .006 9.10 

For details, see supplemental Table 6.

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