Enrichment of BCL6-related gene expression signatures and direct targets in DS-ALL profile genes (FDR < 15%)
. | Size . | P . | Q-value . |
---|---|---|---|
Oncomine “Molecular Concepts” enriched in DS-ALL up-regulated genes | |||
EREB lymphoblastoid cell line BCL6 transfection top 10% overexpressed30 | 17 | .004 | 0.093 |
Ramos Burkitt lymphoma cell line BCL6 pest mutant top 5% underexpressed in anti-IgM30 | 11 | .011 | 0.138 |
Lymphoma BCL6 break top 5% overexpressed31 | 11 | .019 | 0.138 |
Lymphoma BCL6 break top 10% overexpressed31 | 17 | .022 | 0.138 |
BCL6 direct targets32 | 11 | .030 | 0.147 |
Oncomine “Molecular Concepts” enriched in DS-ALL down-regulated genes | |||
Lymphoma BCL6 break top 10% underexpressed31 | 36 | < .001 | 0.001 |
EREB lymphoblastoid cell line BCL6 transfection top 10% underexpressed30 | 26 | < .001 | 0.001 |
Lymphoma BCL6 break top 5% underexpressed31 | 20 | .001 | 0.008 |
. | Size . | P . | Q-value . |
---|---|---|---|
Oncomine “Molecular Concepts” enriched in DS-ALL up-regulated genes | |||
EREB lymphoblastoid cell line BCL6 transfection top 10% overexpressed30 | 17 | .004 | 0.093 |
Ramos Burkitt lymphoma cell line BCL6 pest mutant top 5% underexpressed in anti-IgM30 | 11 | .011 | 0.138 |
Lymphoma BCL6 break top 5% overexpressed31 | 11 | .019 | 0.138 |
Lymphoma BCL6 break top 10% overexpressed31 | 17 | .022 | 0.138 |
BCL6 direct targets32 | 11 | .030 | 0.147 |
Oncomine “Molecular Concepts” enriched in DS-ALL down-regulated genes | |||
Lymphoma BCL6 break top 10% underexpressed31 | 36 | < .001 | 0.001 |
EREB lymphoblastoid cell line BCL6 transfection top 10% underexpressed30 | 26 | < .001 | 0.001 |
Lymphoma BCL6 break top 5% underexpressed31 | 20 | .001 | 0.008 |