Cellular composition in B6 and T-bet−/− mice
| Measurements . | B6 . | T-bet−/− . | P . |
|---|---|---|---|
| N (M + F) | 6 + 3 = 9 | 859 ± 42 | |
| Peripheral blood | |||
| WBCs, ×106/mL | 9.9 ± 0.8 | 7.6 ± 0.6 | .04 |
| Neutrophils, ×106/mL | 1.9 ± 0.6 | 2.1 ± 0.5 | .81 |
| Lymphocytes, ×106/mL | 7.7 ± 0.7 | 5.3 ± 0.5 | .01 |
| RBCs, ×109/mL | 9.8 ± 0.2 | 9.0 ± 0.2 | .01 |
| Platelets, ×106/mL | 925 ± 56 | 859 ± 42 | .36 |
| CD4, % | 12.4 ± 1.2 | 9.2 ± 0.9 | .06 |
| CD8, % | 9.1 ± 0.8 | 7.6 ± 0.6 | .15 |
| Bone marrow | |||
| BM cells, ×106 | 298 ± 27 | 280 ± 21 | .60 |
| LSKCD34−, ×103 | 15.0 ± 2.5 | 12.3 ± 1.9 | .40 |
| CD4, % | 4.2 ± 0.9 | 5.4 ± 0.7 | .30 |
| CD8, % | 3.9 ± 0.4 | 3.0 ± 0.3 | .98 |
| Spleen | |||
| CD4, % | 11.5 ± 1.8 | 12.5 ± 1.4 | .66 |
| CD8, % | 9.8 ± 1.2 | 9.4 ± 0.9 | .75 |
| Lymph nodes | |||
| CD4, % | 33.2 ± 1.7 | 26.8 ± 1.0 | .05 |
| CD8, % | 29.2 ± 1.6 | 29.2 ± 0.9 | .91 |
| Measurements . | B6 . | T-bet−/− . | P . |
|---|---|---|---|
| N (M + F) | 6 + 3 = 9 | 859 ± 42 | |
| Peripheral blood | |||
| WBCs, ×106/mL | 9.9 ± 0.8 | 7.6 ± 0.6 | .04 |
| Neutrophils, ×106/mL | 1.9 ± 0.6 | 2.1 ± 0.5 | .81 |
| Lymphocytes, ×106/mL | 7.7 ± 0.7 | 5.3 ± 0.5 | .01 |
| RBCs, ×109/mL | 9.8 ± 0.2 | 9.0 ± 0.2 | .01 |
| Platelets, ×106/mL | 925 ± 56 | 859 ± 42 | .36 |
| CD4, % | 12.4 ± 1.2 | 9.2 ± 0.9 | .06 |
| CD8, % | 9.1 ± 0.8 | 7.6 ± 0.6 | .15 |
| Bone marrow | |||
| BM cells, ×106 | 298 ± 27 | 280 ± 21 | .60 |
| LSKCD34−, ×103 | 15.0 ± 2.5 | 12.3 ± 1.9 | .40 |
| CD4, % | 4.2 ± 0.9 | 5.4 ± 0.7 | .30 |
| CD8, % | 3.9 ± 0.4 | 3.0 ± 0.3 | .98 |
| Spleen | |||
| CD4, % | 11.5 ± 1.8 | 12.5 ± 1.4 | .66 |
| CD8, % | 9.8 ± 1.2 | 9.4 ± 0.9 | .75 |
| Lymph nodes | |||
| CD4, % | 33.2 ± 1.7 | 26.8 ± 1.0 | .05 |
| CD8, % | 29.2 ± 1.6 | 29.2 ± 0.9 | .91 |
Data shown are means with SEs after variance analysis.
BM indicates bone marrow; RBCs, red blood cells; and WBCs, white blood cells.