Table 1 The IC 50 was calculated for... | American Society of Hematology

Table 1

The IC₅₀ was calculated for each of the cell lines from the data presented in Figure 1 and is shown in micromoles

Line	IC50, μM
Human pre T-LBL cell lines
KOP-TK1	0.83
MOLT16	0.83
ALL-SIL	2.78
HPB-ALL	3.89
TALL-1	4.17
HSB2	7.78
Jurkat	8.89
CEM	15.0
DU528	15.0
SUPT11	27.5
Human non-T leukemic cell lines
MV4-11	3.89
Nalm6	9.17
Kasumi1	12.8
HEL	16.9
U937	21.4
NB4	22.2
HL60	24.4
THP1	28.1
K562	39.7
Murine leukemic cell lines
12/1	3.06
6645/4	3.38
6605/4	3.61
6812/2	6.67
St4113	6.67
F4-6	14.4

Line	IC50, μM
Human pre T-LBL cell lines
KOP-TK1	0.83
MOLT16	0.83
ALL-SIL	2.78
HPB-ALL	3.89
TALL-1	4.17
HSB2	7.78
Jurkat	8.89
CEM	15.0
DU528	15.0
SUPT11	27.5
Human non-T leukemic cell lines
MV4-11	3.89
Nalm6	9.17
Kasumi1	12.8
HEL	16.9
U937	21.4
NB4	22.2
HL60	24.4
THP1	28.1
K562	39.7
Murine leukemic cell lines
12/1	3.06
6645/4	3.38
6605/4	3.61
6812/2	6.67
St4113	6.67
F4-6	14.4

IC₅₀ indicates 50% inhibitory concentration; and pre-T-LBL, precursor T-cell lymphoblastic leukemia/lymphoma.