Patient characteristics
| Characteristic . | All patients . | High-dose dexamethasone patients . | ||||
|---|---|---|---|---|---|---|
| thal/dex (n = 183), n (%) . | len/dex (n = 228), n (%) . | P . | thal/dex (n = 72) . | len/dex (n = 72) . | P . | |
| Median age, y (range) | 60.2 (22.2-79.5) | 62.9 (29.0-92.9) | .061 | 63.3 (36.6-78.7) | 63.5 (29.0-78.4) | .952 |
| Less than 65 y | 125 (68.3) | 127 (55.7) | .009 | 40 (55.6) | 40 (55.6) | > .999 |
| Male sex | 109 (59.6) | 142 (62.3) | .574 | 44 (61.1) | 43 (59.7) | .865 |
| International Staging System | ||||||
| I/II* | 95 (75.4) | 151 (77.4) | .673 | 41 (71.9) | 53 (81.5) | .208 |
| III* | 31 (24.6) | 44 (22.6) | .673 | 16 (28.1) | 12 (18.5) | .208 |
| Missing | 57 (31.2) | 33 (14.5) | — | 15 (20.8) | 7 (9.7) | — |
| Type of M protein | ||||||
| IgG | 105 (57.4) | 136 (59.6) | .642 | 45 (62.5) | 40 (55.6) | .397 |
| IgA | 34 (18.6) | 43 (18.9) | .942 | 18 (25.0) | 17 (23.6) | .846 |
| No serum M protein | 2 (1.1) | 4 (1.8) | .696 | 0 (0) | 1 (1.4) | > .999 |
| Biclonal | 3 (1.6) | 5 (2.2) | .737 | 0 (0) | 2 (2.8) | .497 |
| Light-chain only | 19 (10.4) | 35 (15.4) | .138 | 5 (6.9) | 9 (12.5) | .400 |
| Missing | 20 (10.9) | 5 (2.2) | — | 4 (5.6) | 3 (4.2) | — |
| Cytogenetic | ||||||
| High-risk* | 17 (37.8) | 25 (32.9) | .586 | 4 (40.0) | 9 (33.3) | .715 |
| Data missing | 138 (75.4) | 152 (66.7) | — | 62 (86.1) | 45 (62.5) | — |
| Treatment | ||||||
| High-dose dexamethasone | 135 (73.7) | 72 (31.6) | < .001 | 72 (100) | 72 (100) | > .999 |
| Transplantation | 110 (60.1) | 111 (48.7) | .021 | 37 (51.4) | 37 (51.4) | > .999 |
| Characteristic . | All patients . | High-dose dexamethasone patients . | ||||
|---|---|---|---|---|---|---|
| thal/dex (n = 183), n (%) . | len/dex (n = 228), n (%) . | P . | thal/dex (n = 72) . | len/dex (n = 72) . | P . | |
| Median age, y (range) | 60.2 (22.2-79.5) | 62.9 (29.0-92.9) | .061 | 63.3 (36.6-78.7) | 63.5 (29.0-78.4) | .952 |
| Less than 65 y | 125 (68.3) | 127 (55.7) | .009 | 40 (55.6) | 40 (55.6) | > .999 |
| Male sex | 109 (59.6) | 142 (62.3) | .574 | 44 (61.1) | 43 (59.7) | .865 |
| International Staging System | ||||||
| I/II* | 95 (75.4) | 151 (77.4) | .673 | 41 (71.9) | 53 (81.5) | .208 |
| III* | 31 (24.6) | 44 (22.6) | .673 | 16 (28.1) | 12 (18.5) | .208 |
| Missing | 57 (31.2) | 33 (14.5) | — | 15 (20.8) | 7 (9.7) | — |
| Type of M protein | ||||||
| IgG | 105 (57.4) | 136 (59.6) | .642 | 45 (62.5) | 40 (55.6) | .397 |
| IgA | 34 (18.6) | 43 (18.9) | .942 | 18 (25.0) | 17 (23.6) | .846 |
| No serum M protein | 2 (1.1) | 4 (1.8) | .696 | 0 (0) | 1 (1.4) | > .999 |
| Biclonal | 3 (1.6) | 5 (2.2) | .737 | 0 (0) | 2 (2.8) | .497 |
| Light-chain only | 19 (10.4) | 35 (15.4) | .138 | 5 (6.9) | 9 (12.5) | .400 |
| Missing | 20 (10.9) | 5 (2.2) | — | 4 (5.6) | 3 (4.2) | — |
| Cytogenetic | ||||||
| High-risk* | 17 (37.8) | 25 (32.9) | .586 | 4 (40.0) | 9 (33.3) | .715 |
| Data missing | 138 (75.4) | 152 (66.7) | — | 62 (86.1) | 45 (62.5) | — |
| Treatment | ||||||
| High-dose dexamethasone | 135 (73.7) | 72 (31.6) | < .001 | 72 (100) | 72 (100) | > .999 |
| Transplantation | 110 (60.1) | 111 (48.7) | .021 | 37 (51.4) | 37 (51.4) | > .999 |
Percentages may not total 100 because of rounding.
— indicates not applicable.
Percentage calculated on number of patients for whom data were available.