Change of expression of different surface proteins on stem cells after deletion of Gfi1b
| Surface protein . | Relative expression level . | P . | |
|---|---|---|---|
| Gfi1bfl/fl . | MxCre tg Gfi1bfl/fl . | ||
| Integrin α4 (CD49d) | 1 | 0.48 ± 0.18 | .02 |
| CXCR4 | 1 | 0.53 ± 0.09 | .01 |
| VCAM-1 | 1 | 0.46 ± 0.07 | .01 |
| Integrin β3 (CD61) | 1 | 13.7 ± 1.9 | .02 |
| Integrin β1 (CD29) | 1 | 1.53 ± 0.2 | .05 |
| Surface protein . | Relative expression level . | P . | |
|---|---|---|---|
| Gfi1bfl/fl . | MxCre tg Gfi1bfl/fl . | ||
| Integrin α4 (CD49d) | 1 | 0.48 ± 0.18 | .02 |
| CXCR4 | 1 | 0.53 ± 0.09 | .01 |
| VCAM-1 | 1 | 0.46 ± 0.07 | .01 |
| Integrin β3 (CD61) | 1 | 13.7 ± 1.9 | .02 |
| Integrin β1 (CD29) | 1 | 1.53 ± 0.2 | .05 |
In 3 independent experiments, expression by mean fluorescence level of the different proteins was measured. To facilitate differences in up- or down-regulation of the different proteins, the expression in the Gfi1bfl/fl was set to 1 (n = 3 for all sets). Depicted are mean values and SEM. P values are based on unpaired 2-sided t test.