Concordance of human GWAS for Hb, MCH, and MCHC, and Mouse CHCM QTL
| Candidate gene(s) . | Human chr . | QTL cross . | Mouse Chr . | QTL peak position (Mb) . | CI (Mb) . | MGI gene location (Mb) . |
|---|---|---|---|---|---|---|
| Abo | 9 | MRxSM | 2 | 33.0 | 10.95-52.49 | 26.7 |
| Tmprss6 | 22 | CBy129S1 | 15 | 72.6 | 41.12-84.31 | 78.3 |
| Cdt1 | 16 | 129S1xA (Chcmq13)* | 8 | 120.5 | — | 125.1 |
| March8-Anubl1-Fam21c | 10 | KSxSM | 6 | 116.5 | 63.71-137.88 | 116.3 |
| Ncaph2-Sco2-Tymp-Klhdc7b | 22 | CByx129S1 | 15 | 72.6 | 41.12-84.31 | 89.2 |
| Rcl1 | 9 | KSxSM | 19 | 34.3 | 14.90-37.32 | 29.2 |
| Gcdh | 19 | 129S1xA (Chcmq12) | 8 | 64.9 | 34.25-128.56 | 87.4 |
| Spna1 | 1 | C3xD | 1 | 81.7 | 66.58-195.10 | 176.1 |
| Aldh2 | 12 | BxWSB | 5 | 120.3 | 111.9-139.6 | 122.0 |
| Trafd1 | 12 | BxWSB | 5 | 120.3 | 111.9-139.6 | 121.8 |
| Bysl | 6 | BxWSB | 17 | 32.9 | 39.2-72.4 | 47.7 |
| Candidate gene(s) . | Human chr . | QTL cross . | Mouse Chr . | QTL peak position (Mb) . | CI (Mb) . | MGI gene location (Mb) . |
|---|---|---|---|---|---|---|
| Abo | 9 | MRxSM | 2 | 33.0 | 10.95-52.49 | 26.7 |
| Tmprss6 | 22 | CBy129S1 | 15 | 72.6 | 41.12-84.31 | 78.3 |
| Cdt1 | 16 | 129S1xA (Chcmq13)* | 8 | 120.5 | — | 125.1 |
| March8-Anubl1-Fam21c | 10 | KSxSM | 6 | 116.5 | 63.71-137.88 | 116.3 |
| Ncaph2-Sco2-Tymp-Klhdc7b | 22 | CByx129S1 | 15 | 72.6 | 41.12-84.31 | 89.2 |
| Rcl1 | 9 | KSxSM | 19 | 34.3 | 14.90-37.32 | 29.2 |
| Gcdh | 19 | 129S1xA (Chcmq12) | 8 | 64.9 | 34.25-128.56 | 87.4 |
| Spna1 | 1 | C3xD | 1 | 81.7 | 66.58-195.10 | 176.1 |
| Aldh2 | 12 | BxWSB | 5 | 120.3 | 111.9-139.6 | 122.0 |
| Trafd1 | 12 | BxWSB | 5 | 120.3 | 111.9-139.6 | 121.8 |
| Bysl | 6 | BxWSB | 17 | 32.9 | 39.2-72.4 | 47.7 |
QTL identified in pairwise search for gene interactions; Hb, hemoglobin; MCH, mean cell hemoglobin; MCHC, mean cell hemoglobin concentration; and CHCM, cell hemoglobin concentration mean.