Ang-2 expression in human inflammatory disease
| Diagnosis . | Tissue . | Ang-2 expression* . |
|---|---|---|
| Myeloid dominated | ||
| Abscess with granulation tissue | Brain | +++ |
| Abscess with granulation tissue | Connective tissue | +++ |
| Abscess with granulation tissue | Intervertebral disc | ++ |
| Granulation tissue | Dura mater | + |
| Granulation tissue | Dura mater | ++ |
| Granulation tissue | Intervertebral disc | + |
| Granulation tissue | Intervertebral disc | ++ |
| Granulation tissue | Intervertebral disc | + |
| Granulation tissue | Intervertebral disc | ++ |
| Granulation tissue | Nervous cyst | + |
| Granulation tissue | Skin | + |
| Granulation tissue | Synovial cyst | ++ |
| Spondylodiscitis with granulation tissue | Fibrocartilage | ++ |
| Lymphoid dominated | ||
| Acute vasculitis | Nerve | − |
| Arteritis temporalis | Artery | − |
| Arteritis temporalis | Artery | − |
| Arteritis temporalis | Artery | − |
| Encephalitis | Brain | − |
| Vasculitis | Nerve | − |
| Diagnosis . | Tissue . | Ang-2 expression* . |
|---|---|---|
| Myeloid dominated | ||
| Abscess with granulation tissue | Brain | +++ |
| Abscess with granulation tissue | Connective tissue | +++ |
| Abscess with granulation tissue | Intervertebral disc | ++ |
| Granulation tissue | Dura mater | + |
| Granulation tissue | Dura mater | ++ |
| Granulation tissue | Intervertebral disc | + |
| Granulation tissue | Intervertebral disc | ++ |
| Granulation tissue | Intervertebral disc | + |
| Granulation tissue | Intervertebral disc | ++ |
| Granulation tissue | Nervous cyst | + |
| Granulation tissue | Skin | + |
| Granulation tissue | Synovial cyst | ++ |
| Spondylodiscitis with granulation tissue | Fibrocartilage | ++ |
| Lymphoid dominated | ||
| Acute vasculitis | Nerve | − |
| Arteritis temporalis | Artery | − |
| Arteritis temporalis | Artery | − |
| Arteritis temporalis | Artery | − |
| Encephalitis | Brain | − |
| Vasculitis | Nerve | − |
Data represent type, tissue, and Ang-2 expression from inflamed specimens of 19 patients. Ang-2 expression strongly correlates with myeloid but is absent in lymphoid-dominated inflammation.
Ang-2 expression score: +++ indicates strong; ++, moderate; +, weak; and −, none.