Multivariate logistic regression analyses: risk factors associated with reduced HDL cholesterol, elevated triglycerides, elevated fasting glucose, elevated waist circumference, and high blood pressure
| . | Reduced HDL cholesterol . | Elevated triglycerides . | Elevated fasting glucose . | Elevated waist circumference . | Elevated blood pressure . | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Adjusted OR (95% CI) . | P . | Adjusted OR (95% CI) . | P . | Adjusted OR (95% CI) . | P . | Adjusted OR (95% CI) . | P . | Adjusted OR (95% CI) . | P . | |
| Treatment modality | ||||||||||
| No transplantation, no CNS irradiation (referent) | ||||||||||
| No transplantation, with CNS irradiation | 1.3 (0.5-3.3) | .65 | 1.2 (0.3-5.9) | .63 | 2.4 (0.3-22.2) | .44 | 1.5 (0.4-6.2) | .55 | 0.8 (0.3-2.3) | .63 |
| Transplantation without TBI | 2.4 (0.6-9.6) | .21 | 0.7 (0.1-7.7) | .77 | NA | .98 | 2.0 (0.3-13.5) | .50 | 0.3 (0.1-1.2) | .08 |
| Transplantation with TBI | 2.5 (1.1-5.7) | .02 | 4.5 (1.6-12.5) | .004 | 6.1 (1.1-33.5) | .04 | 1.0 (0.3-3.2) | .93 | 0.8 (0.3-2.0) | .64 |
| Type of leukemia | ||||||||||
| AML (referent) | ||||||||||
| ALL | 1.3 (0.5-3.7) | .57 | 1.0 (0.3-3.4) | .95 | 0.5 (0.1-2.8) | .39 | 1.3 (0.3-6.7) | .74 | 0.4 (0.1-1.2) | .11 |
| Sex | ||||||||||
| Female (referent) | ||||||||||
| Male | 0.8 (0.4-1.6) | .61 | 0.4 (0.2-1.1) | .08 | 4.1 (0.8-21.6) | .10 | 0.5 (0.2-1.3) | .14 | 3.1 (1.5-6.7) | .003 |
| Age at evaluation, y (range) | 1.0 (0.9-1.1) | .85 | 1.1 (1.0-1.2) | .09 | 1.1 (1.0-1.2) | .44 | 1.1 (1.0-1.2) | .21 | 1.1 (1.02-1.2) | .01 |
| . | Reduced HDL cholesterol . | Elevated triglycerides . | Elevated fasting glucose . | Elevated waist circumference . | Elevated blood pressure . | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Adjusted OR (95% CI) . | P . | Adjusted OR (95% CI) . | P . | Adjusted OR (95% CI) . | P . | Adjusted OR (95% CI) . | P . | Adjusted OR (95% CI) . | P . | |
| Treatment modality | ||||||||||
| No transplantation, no CNS irradiation (referent) | ||||||||||
| No transplantation, with CNS irradiation | 1.3 (0.5-3.3) | .65 | 1.2 (0.3-5.9) | .63 | 2.4 (0.3-22.2) | .44 | 1.5 (0.4-6.2) | .55 | 0.8 (0.3-2.3) | .63 |
| Transplantation without TBI | 2.4 (0.6-9.6) | .21 | 0.7 (0.1-7.7) | .77 | NA | .98 | 2.0 (0.3-13.5) | .50 | 0.3 (0.1-1.2) | .08 |
| Transplantation with TBI | 2.5 (1.1-5.7) | .02 | 4.5 (1.6-12.5) | .004 | 6.1 (1.1-33.5) | .04 | 1.0 (0.3-3.2) | .93 | 0.8 (0.3-2.0) | .64 |
| Type of leukemia | ||||||||||
| AML (referent) | ||||||||||
| ALL | 1.3 (0.5-3.7) | .57 | 1.0 (0.3-3.4) | .95 | 0.5 (0.1-2.8) | .39 | 1.3 (0.3-6.7) | .74 | 0.4 (0.1-1.2) | .11 |
| Sex | ||||||||||
| Female (referent) | ||||||||||
| Male | 0.8 (0.4-1.6) | .61 | 0.4 (0.2-1.1) | .08 | 4.1 (0.8-21.6) | .10 | 0.5 (0.2-1.3) | .14 | 3.1 (1.5-6.7) | .003 |
| Age at evaluation, y (range) | 1.0 (0.9-1.1) | .85 | 1.1 (1.0-1.2) | .09 | 1.1 (1.0-1.2) | .44 | 1.1 (1.0-1.2) | .21 | 1.1 (1.02-1.2) | .01 |
NA indicates not applicable.