Table 1 AML1a expression increases... | American Society of Hematology

Table 1

AML1a expression increases secondarily transplantable HSCs

Cell no.*	Unmanipulated BM (1°)	AML1a-transduced BM (1°)	AML1a-transduced BM (2°)
500 000	12/12†	12/12	12/12
200 000	11/11	12/12	12/12
50 000	9/12	12/12	12/12
12 500	3/12	8/10	8/10
3125	0/11	3/10	2/10
HSC	1/39 922‡	1/7 959	1/8,941
95% CI	1/68 165 ∼ 374;1/23 381	1/14 545 ∼ 374;1/4 355	1/16 261 ∼ 374;1/4 916

Cell no.*	Unmanipulated BM (1°)	AML1a-transduced BM (1°)	AML1a-transduced BM (2°)
500 000	12/12†	12/12	12/12
200 000	11/11	12/12	12/12
50 000	9/12	12/12	12/12
12 500	3/12	8/10	8/10
3125	0/11	3/10	2/10
HSC	1/39 922‡	1/7 959	1/8,941
95% CI	1/68 165 ∼ 374;1/23 381	1/14 545 ∼ 374;1/4 355	1/16 261 ∼ 374;1/4 916

Number of “test” cells equivalent to unmanipulated BM cells.

Number of mice positive for engraftment/number of total mice used for the primary transplantation.

The HSC frequency and its 95% CI were calculated using Poisson statistics.