2013 revised response criteria for myeloproliferative neoplasms8,9
. | Essential thrombocythemia . | Polycythemia vera . | Myelofibrosis . |
---|---|---|---|
Complete response | X | X | X |
Partial response | X | X | X |
Clinical improvement | X | ||
Stable disease | X | ||
No response | X | X | |
Relapse | X | ||
Other responses* | Molecular | Molecular | Cytogenetic and molecular |
. | Essential thrombocythemia . | Polycythemia vera . | Myelofibrosis . |
---|---|---|---|
Complete response | X | X | X |
Partial response | X | X | X |
Clinical improvement | X | ||
Stable disease | X | ||
No response | X | X | |
Relapse | X | ||
Other responses* | Molecular | Molecular | Cytogenetic and molecular |
See Table 1 in the article by Takahashi et al that begins on page 3784.
Complete response = eradication of a preexisting abnormality; partial response = >50% decrease in allele burden (with at least 20% mutant allele burden at baseline).
Other responses were measured in peripheral blood granulocytes.