Table 1 Summary of results of treatment... | American Society of Hematology

Table 1

Summary of results of treatment of CD4 T cells with RNA expression constructs

RNA	Telomerase activity level	Dexamethasone-induced apoptosis	Stimulation-associated apoptosis	hTERT-induced apoptosis
shScramble	Normal	Susceptible	Normal	NA
shTERT	Decreased	Resistant	Normal	NA
shTR1,2	Decreased	NA	Increased	NA
WT hTR	Increased	Susceptible	Normal	Susceptible
Δ96-97	Catalytically inactive	NA	Normal	Resistant
G305A	Catalytically inactive	Resistant	Normal	Resistant
hTR-U64	Catalytically inactive	Susceptible	Normal	Susceptible
hTERT	Increased	NA	Increased	NA
β⁻hTERT	Catalytically inactive	NA	Normal	NA

RNA	Telomerase activity level	Dexamethasone-induced apoptosis	Stimulation-associated apoptosis	hTERT-induced apoptosis
shScramble	Normal	Susceptible	Normal	NA
shTERT	Decreased	Resistant	Normal	NA
shTR1,2	Decreased	NA	Increased	NA
WT hTR	Increased	Susceptible	Normal	Susceptible
Δ96-97	Catalytically inactive	NA	Normal	Resistant
G305A	Catalytically inactive	Resistant	Normal	Resistant
hTR-U64	Catalytically inactive	Susceptible	Normal	Susceptible
hTERT	Increased	NA	Increased	NA
β⁻hTERT	Catalytically inactive	NA	Normal	NA

NA, not analyzed. Bold text designates resistance to apoptosis. Italic text designates increased telomerase activity.