List of CXCR4 mutations reported
| Type of mutation . | Nucleotide change . | Amino acid change . | Times reported . | Described in . |
|---|---|---|---|---|
| Frameshift | c.945_946insC | H315fs | 1 | 13 |
| Frameshift | c.952_953insA | T318fs | 4 | 13,14 |
| Frameshift | c.953_954delC | T318fs | 1 | 13 |
| Frameshift | c.963_964insC | R322fs | 2 | 13,14 |
| Frameshift | c.977_978insC | L326fs | 1 | 13 |
| Frameshift | c.979_985delAGATCCT | K327fs | 1 | 13 |
| Frameshift | c.982_983delAT | I328fs | 1 | 13 |
| Nonsense | c.1000 C>T | R334X | 5 | 12-14 |
| Nonsense | c.1006 G>T | G336X | 1 | 13 |
| Nonsense | c.1013 C>A | S338X | 11 | 12-14 |
| Nonsense | c.1013 C>G | S338X | 23 | 12-14, present study |
| Frameshift | c.1012_1013delT | S338fs | 2 | 12,13 |
| Frameshift | c.1012_1015delTCAT | S338fs | 1 | 13 |
| Frameshift | c.1012_1013insT | S338fs | 8 | 13,14, present study |
| Frameshift | c.1017_1018delT | S339fs | 1 | 13 |
| Frameshift | c.1022_1023insT | S341fs | 1 | 13 |
| Nonsense | c.1031_1033delCT | S344X | 1 | 13 |
| Frameshift | c.1117_1127insTGTTTCCACTG | S339fs | 1 | 12 |
| Frameshift | c.1125_1126delCT | T342fs | 3 | 12,14, present study |
| Frameshift | c.1011_1012insA | S338fs | 1 | Present study |
| Missense | c.1006 G>A | G336R | 4 | Present study |
| Missense | c.1016 C>T | S339F | 4 | Present study |
| Frameshift | c.1007delG | G336fs | 2 | Present study |
| Frameshift | c.1002_1024del | R334fs | 1 | Present study |
| Frameshift | c.1002_1003insA | G335fs | 1 | Present study |
| Frameshift | c.970delT | S324fs | 1 | Present study |
| Frameshift | c.931_932insT | T311fs | 1 | 14 |
| Frameshift | c.951_955delACCTC | T318fs | 2 | 14 |
| Frameshift | c.954_955insC | S319fs | 1 | 14 |
| Frameshift | c.958_960delTG | V320fs | 1 | 14 |
| Frameshift | c.969_970insG | S324fs | 1 | 14 |
| Frameshift | c.978_979insT | K327fs | 1 | 14 |
| Frameshift | c.984_985insT | L329fs | 1 | 14 |
| Frameshift | c.993_994insA | G332fs | 1 | 14 |
| Frameshift | c.1005_1006insT | G336fs | 1 | 14 |
| Frameshift | c.1013_1016delATCT | S338fs | 2 | 14 |
| Frameshift | c.1013_1030delATCTGTTTCCACTGAGT | S338fs | 1 | 14 |
| Frameshift | c.1015_1017delCT | S339fs | 1 | 14 |
| Frameshift | c.1020_1021delT | S341fs | 1 | 14 |
| Frameshift | c.1030_1041CTGAGTCTTC>GT | S344fs | 1 | 14 |
| Frameshift | c.1033_1035delAG | E345fs | 1 | 14 |
| Nonsense | c.997 A>T | K333X | 1 | 14 |
| Type of mutation . | Nucleotide change . | Amino acid change . | Times reported . | Described in . |
|---|---|---|---|---|
| Frameshift | c.945_946insC | H315fs | 1 | 13 |
| Frameshift | c.952_953insA | T318fs | 4 | 13,14 |
| Frameshift | c.953_954delC | T318fs | 1 | 13 |
| Frameshift | c.963_964insC | R322fs | 2 | 13,14 |
| Frameshift | c.977_978insC | L326fs | 1 | 13 |
| Frameshift | c.979_985delAGATCCT | K327fs | 1 | 13 |
| Frameshift | c.982_983delAT | I328fs | 1 | 13 |
| Nonsense | c.1000 C>T | R334X | 5 | 12-14 |
| Nonsense | c.1006 G>T | G336X | 1 | 13 |
| Nonsense | c.1013 C>A | S338X | 11 | 12-14 |
| Nonsense | c.1013 C>G | S338X | 23 | 12-14, present study |
| Frameshift | c.1012_1013delT | S338fs | 2 | 12,13 |
| Frameshift | c.1012_1015delTCAT | S338fs | 1 | 13 |
| Frameshift | c.1012_1013insT | S338fs | 8 | 13,14, present study |
| Frameshift | c.1017_1018delT | S339fs | 1 | 13 |
| Frameshift | c.1022_1023insT | S341fs | 1 | 13 |
| Nonsense | c.1031_1033delCT | S344X | 1 | 13 |
| Frameshift | c.1117_1127insTGTTTCCACTG | S339fs | 1 | 12 |
| Frameshift | c.1125_1126delCT | T342fs | 3 | 12,14, present study |
| Frameshift | c.1011_1012insA | S338fs | 1 | Present study |
| Missense | c.1006 G>A | G336R | 4 | Present study |
| Missense | c.1016 C>T | S339F | 4 | Present study |
| Frameshift | c.1007delG | G336fs | 2 | Present study |
| Frameshift | c.1002_1024del | R334fs | 1 | Present study |
| Frameshift | c.1002_1003insA | G335fs | 1 | Present study |
| Frameshift | c.970delT | S324fs | 1 | Present study |
| Frameshift | c.931_932insT | T311fs | 1 | 14 |
| Frameshift | c.951_955delACCTC | T318fs | 2 | 14 |
| Frameshift | c.954_955insC | S319fs | 1 | 14 |
| Frameshift | c.958_960delTG | V320fs | 1 | 14 |
| Frameshift | c.969_970insG | S324fs | 1 | 14 |
| Frameshift | c.978_979insT | K327fs | 1 | 14 |
| Frameshift | c.984_985insT | L329fs | 1 | 14 |
| Frameshift | c.993_994insA | G332fs | 1 | 14 |
| Frameshift | c.1005_1006insT | G336fs | 1 | 14 |
| Frameshift | c.1013_1016delATCT | S338fs | 2 | 14 |
| Frameshift | c.1013_1030delATCTGTTTCCACTGAGT | S338fs | 1 | 14 |
| Frameshift | c.1015_1017delCT | S339fs | 1 | 14 |
| Frameshift | c.1020_1021delT | S341fs | 1 | 14 |
| Frameshift | c.1030_1041CTGAGTCTTC>GT | S344fs | 1 | 14 |
| Frameshift | c.1033_1035delAG | E345fs | 1 | 14 |
| Nonsense | c.997 A>T | K333X | 1 | 14 |