Table 4 Myc rearrangement and... | American Society of Hematology

Table 4

Myc rearrangement and gain/amplification in pediatric DLBCL

Case ID	Pathologic diagnosis	Molecular diagnosis by GEP		Age, y	Sex	t(8;14)	8q24 CN
Case ID	Pathologic diagnosis	BL vs DLBCL	DLBCL subgroup	Age, y	Sex	t(8;14)	8q24 CN
P01	DLBCL	DLBCL	GCB	9	M	−	3-4
P02	DLBCL	DLBCL	GCB	10	M	−	3-5
P03	DLBCL	DLBCL	GCB	13	M	−	3-4
P04	DLBCL	DLBCL	GCB	18	F	−	ND
P05	DLBCL	DLBCL	PMBL	15	F	−	2
P06	DLBCL	DLBCL	UC	11	M	−	2
P07	DLBCL	DLBCL	UC	18	M	+	3-4
P08	BL	DLBCL	ABC	2	M	+	2
P09	BL	DLBCL	UC	11	F	+	3
P10	BL	DLBCL	GCB	6	M	+	ND
P11	BL	DLBCL	GCB	4	F	+	2
P12	BL	DLBCL	GCB	10	M	−	2
P13	BL	DLBCL	GCB	10	F	−	3-4
P14	BL	DLBCL	GCB	2	M	−	2
P15	BL	DLBCL	GCB	5	M	−	3
P16	BL	DLBCL	GCB	6	M	ND	Amplification
P17	BL	DLBCL	GCB	12	M	−	ND

Case ID	Pathologic diagnosis	Molecular diagnosis by GEP		Age, y	Sex	t(8;14)	8q24 CN
Case ID	Pathologic diagnosis	BL vs DLBCL	DLBCL subgroup	Age, y	Sex	t(8;14)	8q24 CN
P01	DLBCL	DLBCL	GCB	9	M	−	3-4
P02	DLBCL	DLBCL	GCB	10	M	−	3-5
P03	DLBCL	DLBCL	GCB	13	M	−	3-4
P04	DLBCL	DLBCL	GCB	18	F	−	ND
P05	DLBCL	DLBCL	PMBL	15	F	−	2
P06	DLBCL	DLBCL	UC	11	M	−	2
P07	DLBCL	DLBCL	UC	18	M	+	3-4
P08	BL	DLBCL	ABC	2	M	+	2
P09	BL	DLBCL	UC	11	F	+	3
P10	BL	DLBCL	GCB	6	M	+	ND
P11	BL	DLBCL	GCB	4	F	+	2
P12	BL	DLBCL	GCB	10	M	−	2
P13	BL	DLBCL	GCB	10	F	−	3-4
P14	BL	DLBCL	GCB	2	M	−	2
P15	BL	DLBCL	GCB	5	M	−	3
P16	BL	DLBCL	GCB	6	M	ND	Amplification
P17	BL	DLBCL	GCB	12	M	−	ND

The abnormal range for MYC rearrangement is 15%-100%. The abnormal range for MYC amplification is 10%-100%. The abnormal range for multiple copies of 8q24 is 10%-100%.

UC indicates unclassifiable DLBCL; and ND, not determined.

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