Maximum NPL obtained after the removal of high LD SNPs for phase 1, phase 2, and the combined dataset of 206 pedigrees
| Chromosome . | Affection status = CLL + LPD, 206 families, NPL score (position Mb) . | Affection status = CLL, 182 families, NPL score (position Mb) . | ||||
|---|---|---|---|---|---|---|
| Phase 1 . | Phase 2 . | Combined . | Phase 1 . | Phase 2 . | Combined . | |
| n | 105 | 101 | 206 | 91 | 91 | 182 |
| 1 | 1.12 (91.5) | 1.41 (80.3) | 1.35 (80.3) | 0.96 (81.6) | 1.09 (80.3) | 1.05 (191.1) |
| 2 | 1.64 (135.3) | 2.60 (134.6) | 3.02 (134.6) | 1.67 (135.3) | 2.31 (134.6) | 2.84 (134.6) |
| 3 | 1.64 (58.0) | 0.99 (193.6) | 1.02 (109.5) | 1.44 (57.7) | 0.79 (103.8) | 0.97 (144.4) |
| 4 | 0.03 (178.6) | 2.22 (36.8) | 1.35 (71.2) | 0.00* | 2.19 (36.8) | 0.99 (67.4) |
| 5 | 1.95 (110.6) | 2.00 (171.9) | 2.12 (124.4) | 1.89 (108.7) | 2.18 (170.4) | 2.37 (109.0) |
| 6 | 2.16 (18.5) | 2.02 (31.6) | 2.80 (29.1) | 1.86 (131.4) | 1.81 (29.4) | 2.44 (29.1) |
| 7 | 0.99 (66.8) | 1.55 (128.3) | 1.29 (127.3) | 0.58 (78.7) | 2.45 (128.3) | 2.00 (127.3) |
| 8 | 0.70 (130.6) | 1.64 (50.9) | 1.55 (50.9) | 0.85 (27.4) | 1.66 (51.6) | 1.51 (50.9) |
| 9 | 0.02 (38.3) | 1.36 (34.6) | 1.03 (35.0) | 0.00* | 0.89 (0.2) | 0.39 (0.5) |
| 10 | 1.80 (118.0) | 1.27 (124.2) | 1.69 (123.4) | 1.59 (117.3) | 1.77 (124.2) | 1.93 (123.4) |
| 11 | 2.66 (48.7) | 1.22 (109.1) | 1.79 (59.5) | 2.75 (51.2) | 1.57 (109.1) | 1.54 (58.4) |
| 12 | 0.89 (97.3) | 2.14 (113.1) | 1.77 (112.5) | 0.79 (97.3) | 2.02 (112.5) | 1.75 (112.5) |
| 13 | 1.70 (42.2) | 1.85 (101.4) | 1.00 (85.1) | 1.21 (42.2) | 1.52 (85.1) | 1.78 (85.1) |
| 14 | 1.60 (102.7) | 0.30 (23.9) | 0.30 (25.5) | 1.28 (98.9) | 0.37 (26.5) | 0.74 (25.5) |
| 15 | 0.60 (59.3) | 1.27 (76.8) | 0.97 (60.2) | 0.64 (59.2) | 1.74 (55.9) | 1.62 (55.9) |
| 16 | 1.51 (68.5) | 1.45 (75.6) | 1.75 (75.4) | 1.16 (61.5) | 1.69 (76.4) | 1.58 (76.4) |
| 17 | 0.00* | 1.26 (11.7) | 0.57 (20.1) | 0.00* | 1.77 (3.9) | 0.79 (20.1) |
| 18 | 1.28 (46.0) | 2.81 (42.5) | 2.66 (42.5) | 1.10 (46.0) | 2.29 (41.8) | 2.21 (41.8) |
| 19 | 1.19 (56.2) | 1.58 (39.0) | 0.91 (56.2) | 0.84 (56.0) | 1.51 (39.0) | 0.84 (56.0) |
| 20 | 0.00* | 1.94 (59.2) | 0.80 (55.8) | 0.23 (8.5) | 2.18 (10.6) | 1.48 (8.5) |
| 21 | 0.00* | 0.63 (23.3) | 0.00* | 0.00* | 0.25 (23.5) | 0.00* |
| 22 | 0.00* | 0.77 (27.8) | 0.00* | 0.00* | 0.44 (33.5) | 0.00* |
| Chromosome . | Affection status = CLL + LPD, 206 families, NPL score (position Mb) . | Affection status = CLL, 182 families, NPL score (position Mb) . | ||||
|---|---|---|---|---|---|---|
| Phase 1 . | Phase 2 . | Combined . | Phase 1 . | Phase 2 . | Combined . | |
| n | 105 | 101 | 206 | 91 | 91 | 182 |
| 1 | 1.12 (91.5) | 1.41 (80.3) | 1.35 (80.3) | 0.96 (81.6) | 1.09 (80.3) | 1.05 (191.1) |
| 2 | 1.64 (135.3) | 2.60 (134.6) | 3.02 (134.6) | 1.67 (135.3) | 2.31 (134.6) | 2.84 (134.6) |
| 3 | 1.64 (58.0) | 0.99 (193.6) | 1.02 (109.5) | 1.44 (57.7) | 0.79 (103.8) | 0.97 (144.4) |
| 4 | 0.03 (178.6) | 2.22 (36.8) | 1.35 (71.2) | 0.00* | 2.19 (36.8) | 0.99 (67.4) |
| 5 | 1.95 (110.6) | 2.00 (171.9) | 2.12 (124.4) | 1.89 (108.7) | 2.18 (170.4) | 2.37 (109.0) |
| 6 | 2.16 (18.5) | 2.02 (31.6) | 2.80 (29.1) | 1.86 (131.4) | 1.81 (29.4) | 2.44 (29.1) |
| 7 | 0.99 (66.8) | 1.55 (128.3) | 1.29 (127.3) | 0.58 (78.7) | 2.45 (128.3) | 2.00 (127.3) |
| 8 | 0.70 (130.6) | 1.64 (50.9) | 1.55 (50.9) | 0.85 (27.4) | 1.66 (51.6) | 1.51 (50.9) |
| 9 | 0.02 (38.3) | 1.36 (34.6) | 1.03 (35.0) | 0.00* | 0.89 (0.2) | 0.39 (0.5) |
| 10 | 1.80 (118.0) | 1.27 (124.2) | 1.69 (123.4) | 1.59 (117.3) | 1.77 (124.2) | 1.93 (123.4) |
| 11 | 2.66 (48.7) | 1.22 (109.1) | 1.79 (59.5) | 2.75 (51.2) | 1.57 (109.1) | 1.54 (58.4) |
| 12 | 0.89 (97.3) | 2.14 (113.1) | 1.77 (112.5) | 0.79 (97.3) | 2.02 (112.5) | 1.75 (112.5) |
| 13 | 1.70 (42.2) | 1.85 (101.4) | 1.00 (85.1) | 1.21 (42.2) | 1.52 (85.1) | 1.78 (85.1) |
| 14 | 1.60 (102.7) | 0.30 (23.9) | 0.30 (25.5) | 1.28 (98.9) | 0.37 (26.5) | 0.74 (25.5) |
| 15 | 0.60 (59.3) | 1.27 (76.8) | 0.97 (60.2) | 0.64 (59.2) | 1.74 (55.9) | 1.62 (55.9) |
| 16 | 1.51 (68.5) | 1.45 (75.6) | 1.75 (75.4) | 1.16 (61.5) | 1.69 (76.4) | 1.58 (76.4) |
| 17 | 0.00* | 1.26 (11.7) | 0.57 (20.1) | 0.00* | 1.77 (3.9) | 0.79 (20.1) |
| 18 | 1.28 (46.0) | 2.81 (42.5) | 2.66 (42.5) | 1.10 (46.0) | 2.29 (41.8) | 2.21 (41.8) |
| 19 | 1.19 (56.2) | 1.58 (39.0) | 0.91 (56.2) | 0.84 (56.0) | 1.51 (39.0) | 0.84 (56.0) |
| 20 | 0.00* | 1.94 (59.2) | 0.80 (55.8) | 0.23 (8.5) | 2.18 (10.6) | 1.48 (8.5) |
| 21 | 0.00* | 0.63 (23.3) | 0.00* | 0.00* | 0.25 (23.5) | 0.00* |
| 22 | 0.00* | 0.77 (27.8) | 0.00* | 0.00* | 0.44 (33.5) | 0.00* |
Where NPLs were 0, SNP marker identifier is not shown.