Genotyped SNPs in HLA-A exons 2 and 3
| SNP . | SNP position IMGT/HLA database . | Amino acid residue* . | Residue position . | Potential contact position† . |
|---|---|---|---|---|
| Exon 2 | ||||
| ––––rs1136657 | 78 | Ser | 26 | — |
| ––––rs12721675 | 144 | Ala | 48 | Peptide |
| ––––rs707910 | 203 | Lys/Arg | 68 | — |
| ––––rs3173427 | 240 | Gly | 80 | — |
| ––––rs3179180 | 256 | Arg/Gly | 86 | TCR/peptide |
| ––––rs3200132 | 257 | Arg/Gln/Lue | 86 | TCR/peptide |
| ––––rs3173426 | 270 | Asn/Lys | 90 | TCR/peptide |
| ––––rs707909 | 271 | Met/Val | 91 | TCR/peptide |
| ––––rs12721692 | 292 | Asp/His | 98 | Peptide |
| ––––rs3129019 | 299 | Ala/Glu/Val | 100 | TCR |
| ––––rs3200156 | 301 | Asn/Asp | 101 | Peptide |
| Exon 3 | ||||
| ––––rs1071743 | 355 | Ile/Lue/Val | 119 | Peptide |
| ––––rs3180267 | 362 | Ile/Arg | 121 | Peptide |
| ––––rs1136695 | 363 | Ile/Met | 121 | Peptide |
| ––––rs1136700 | 385 | Pro/Ser | 129 | — |
| ––––rs3179191 | 391 | Gly/Trp | 131 | — |
| ––––rs3173420 | 413 | Arg/Gln | 138 | Peptide |
| ––––rs12721717 | 414 | Arg | 138 | Peptide |
| ––––rs3173419 | 418 | Asp/Tyr | 140 | Peptide |
| ––––rs1059509 | 453 | Asn/Lys | 151 | — |
| ––––rs1059514 | 489 | Ala | 163 | — |
| ––––rs1059516 | 497 | Ile/Thr | 166 | — |
| ––––rs1059520 | 506 | Arg/His | 169 | TCR |
| ––––rs9260154 | 521 | Val/ Ala | 174 | TCR |
| ––––rs9256983 | 527 | Ala/Val/Glu | 176 | TCR/peptide |
| ––––rs9260155 | 538 | Lue | 180 | Peptide |
| ––––rs9260156 | 539 | Lue/Ter/Trp | 180 | Peptide |
| ––––rs9260157 | 545 | Val/Ala | 182 | TCR |
| ––––rs3129018 | 559 | Pro/Thr | 187 | TCR/peptide |
| ––––rs9260159 | 560 | Arg/Thr | 187 | TCR/peptide |
| ––––rs9260160 | 570 | Asp/Glu | 190 | TCR |
| ––––rs3098019 | 571 | Gly/Trp | 191 | TCR/peptide |
| SNP . | SNP position IMGT/HLA database . | Amino acid residue* . | Residue position . | Potential contact position† . |
|---|---|---|---|---|
| Exon 2 | ||||
| ––––rs1136657 | 78 | Ser | 26 | — |
| ––––rs12721675 | 144 | Ala | 48 | Peptide |
| ––––rs707910 | 203 | Lys/Arg | 68 | — |
| ––––rs3173427 | 240 | Gly | 80 | — |
| ––––rs3179180 | 256 | Arg/Gly | 86 | TCR/peptide |
| ––––rs3200132 | 257 | Arg/Gln/Lue | 86 | TCR/peptide |
| ––––rs3173426 | 270 | Asn/Lys | 90 | TCR/peptide |
| ––––rs707909 | 271 | Met/Val | 91 | TCR/peptide |
| ––––rs12721692 | 292 | Asp/His | 98 | Peptide |
| ––––rs3129019 | 299 | Ala/Glu/Val | 100 | TCR |
| ––––rs3200156 | 301 | Asn/Asp | 101 | Peptide |
| Exon 3 | ||||
| ––––rs1071743 | 355 | Ile/Lue/Val | 119 | Peptide |
| ––––rs3180267 | 362 | Ile/Arg | 121 | Peptide |
| ––––rs1136695 | 363 | Ile/Met | 121 | Peptide |
| ––––rs1136700 | 385 | Pro/Ser | 129 | — |
| ––––rs3179191 | 391 | Gly/Trp | 131 | — |
| ––––rs3173420 | 413 | Arg/Gln | 138 | Peptide |
| ––––rs12721717 | 414 | Arg | 138 | Peptide |
| ––––rs3173419 | 418 | Asp/Tyr | 140 | Peptide |
| ––––rs1059509 | 453 | Asn/Lys | 151 | — |
| ––––rs1059514 | 489 | Ala | 163 | — |
| ––––rs1059516 | 497 | Ile/Thr | 166 | — |
| ––––rs1059520 | 506 | Arg/His | 169 | TCR |
| ––––rs9260154 | 521 | Val/ Ala | 174 | TCR |
| ––––rs9256983 | 527 | Ala/Val/Glu | 176 | TCR/peptide |
| ––––rs9260155 | 538 | Lue | 180 | Peptide |
| ––––rs9260156 | 539 | Lue/Ter/Trp | 180 | Peptide |
| ––––rs9260157 | 545 | Val/Ala | 182 | TCR |
| ––––rs3129018 | 559 | Pro/Thr | 187 | TCR/peptide |
| ––––rs9260159 | 560 | Arg/Thr | 187 | TCR/peptide |
| ––––rs9260160 | 570 | Asp/Glu | 190 | TCR |
| ––––rs3098019 | 571 | Gly/Trp | 191 | TCR/peptide |