CCR1 expression is increased on CD4+ and CD8+ T cells following allo-SCT
. | Day 7 . | Day 11 . | ||||
---|---|---|---|---|---|---|
Naive | Syn | Allo | Naive | Syn | Allo | |
CD4+ | 6.9 | 8.6 ± 1.6 | 16.5 ± 2.6 | 3.0 | 8.6 ± 2.3 | 33.6 ± 1.8* |
CD8+ | 3.5 | 7.3 ± 1.8 | 42.1 ± 2.2* | 2.5 | 10.3 ± 0.9 | 52.3 ± 1.6* |
. | Day 7 . | Day 11 . | ||||
---|---|---|---|---|---|---|
Naive | Syn | Allo | Naive | Syn | Allo | |
CD4+ | 6.9 | 8.6 ± 1.6 | 16.5 ± 2.6 | 3.0 | 8.6 ± 2.3 | 33.6 ± 1.8* |
CD8+ | 3.5 | 7.3 ± 1.8 | 42.1 ± 2.2* | 2.5 | 10.3 ± 0.9 | 52.3 ± 1.6* |
The percentage of the total CD4+ and CD8+ cells expressing CCR1: (CD4+CCR1+)/[CD4+ + (CD4+ CCR1+)] and (CD8+ CCR1+)/[CD8+ + (CD8+CCR1+)] was increased at each time point following allo-SCT. Data are presented as means plus SEM and represent a combination of 2 similar experiments.
Syn indicates syngeneic.
P < .001 (allo-SCT compared with syngeneic controls).