Characteristics and risk factors for cardiovascular disease in patients treated with allogeneic and autologous HSCT
| Characteristics numbers . | Allogeneic HSCT n =265 . | Autologous HSCT n =145 . | P . |
|---|---|---|---|
| Male, no. (%) | 145 (55%) | 87 (60%) | .302 |
| Median age at transplantation, y (range) | 27 (2-60) | 44.5 (2-69) | <.001 |
| Median age at last follow-up, y (range) | 39 (6-66) | 49 (3-72) | <.001 |
| Median time of follow-up, y (range) | 9 (2-24) | 5 (2-16) | <.001 |
| Alive at last follow-up, no. (%) | 208 (78%) | 111 (77%) | .652 |
| Disease and transplant-related factors, no. (%) | <.001 | ||
| Acute myeloid leukemia | 79 (30%) | 5 (3.5%) | — |
| Chronic myeloid leukemia | 75 (28%) | 2 (1.5%) | — |
| Myelodysplastic or myeloproliferative syndrome | 17 (6.5%) | 3 (2%) | — |
| Acute lymphoid leukemia | 51 (19%) | 8 (5.5%) | — |
| Mature lymphoid neoplasia | 19 (7.5%) | 88 (61%) | — |
| Aplastic anemia | 24 (9%) | 0 | — |
| Solid tumor | 0 | 32 (22%) | — |
| Autoimmune disease | 0 | 7 (4.5%) | — |
| Total body irradiation for conditioning, no. (%) | <.001 | ||
| No | 36 (14%) | 126 (87%) | — |
| Yes | 229 (86%) | 19 (13%) | — |
| Risk factors for atherosclerosis at diagnosis, no. (%) | |||
| Arterial hypertension | 11/254 (4.3%) | 23/144 (16%) | <.001 |
| Diabetes | 2/250 (0.8%) | 4/145 (2.8%) | .197 |
| Dyslipidemia | 29/232 (12.6%) | 38/135 (28.4%) | <.001 |
| Body mass index over 25 kg/m2 | 45/245 (18.4%) | 50/142 (35.2%) | .001 |
| Characteristics numbers . | Allogeneic HSCT n =265 . | Autologous HSCT n =145 . | P . |
|---|---|---|---|
| Male, no. (%) | 145 (55%) | 87 (60%) | .302 |
| Median age at transplantation, y (range) | 27 (2-60) | 44.5 (2-69) | <.001 |
| Median age at last follow-up, y (range) | 39 (6-66) | 49 (3-72) | <.001 |
| Median time of follow-up, y (range) | 9 (2-24) | 5 (2-16) | <.001 |
| Alive at last follow-up, no. (%) | 208 (78%) | 111 (77%) | .652 |
| Disease and transplant-related factors, no. (%) | <.001 | ||
| Acute myeloid leukemia | 79 (30%) | 5 (3.5%) | — |
| Chronic myeloid leukemia | 75 (28%) | 2 (1.5%) | — |
| Myelodysplastic or myeloproliferative syndrome | 17 (6.5%) | 3 (2%) | — |
| Acute lymphoid leukemia | 51 (19%) | 8 (5.5%) | — |
| Mature lymphoid neoplasia | 19 (7.5%) | 88 (61%) | — |
| Aplastic anemia | 24 (9%) | 0 | — |
| Solid tumor | 0 | 32 (22%) | — |
| Autoimmune disease | 0 | 7 (4.5%) | — |
| Total body irradiation for conditioning, no. (%) | <.001 | ||
| No | 36 (14%) | 126 (87%) | — |
| Yes | 229 (86%) | 19 (13%) | — |
| Risk factors for atherosclerosis at diagnosis, no. (%) | |||
| Arterial hypertension | 11/254 (4.3%) | 23/144 (16%) | <.001 |
| Diabetes | 2/250 (0.8%) | 4/145 (2.8%) | .197 |
| Dyslipidemia | 29/232 (12.6%) | 38/135 (28.4%) | <.001 |
| Body mass index over 25 kg/m2 | 45/245 (18.4%) | 50/142 (35.2%) | .001 |
— indicates not applicable.