Table 3 Summary of GPIIIa peptides... | American Society of Hematology

Table 3

Summary of GPIIIa peptides eliciting PBMC proliferation from AITP patients in vitro

Patient with AITP	Platelet count at testing, × 10⁹/L	HLA-DR type DRB1*	HLA-DQ type DQB1*	Anti-GPIIb/IIIa status		Stimulatory peptides, SI > 3
Patient with AITP	Platelet count at testing, × 10⁹/L	HLA-DR type DRB1*	HLA-DQ type DQB1*	Serum	Eluate	Stimulatory peptides, SI > 3
AITP1	10	03/11	02/03	Pos	wPos	2, 3, 44, 53, 68, 81, 82
AITP2	102	07/11	02/03	Pos	wPos	42, 49, 50, 58, 60, 67, 70, 71, 72, 73, 74, 77, 78, 80, 81
AITP3	3	01/01	05/05	Pos	Pos	2, 44, 50, 80, 82*
AITP4	14	01/04	03/05	Neg	NT	72, 82*
AITP5	163	03/04	02/03	Neg	Pos	82*
AITP6	33	03/07	02/03	Neg	NT	None
AITP7	3	03/03	02/02	Pos	Pos	8, 11, 14, 15, 35, 40, 47, 56, 70, 82*
AITP8	16	03/07	02/02	Neg	NT	29, 34, 35, 36, 40, 44, 5, 77*, 78, 80, 81
AITP9	338	15/15	06/06	Neg	Pos	2, 6, 7, 14, 15, 30, 46, 47, 53, 82
AITP10	394	01/03	02/05	Pos	wPos	2, 3, 44, 47, 53, 82*
AITP11	177	04/13	03/06	Pos	Pos	2, 32, 47, 53, 77, 82*, 86
AITP12	170	03/04	02/03	Pos	Pos	9, 17, 31, 53, 81, 82
AITP13	127	NT	NT	Pos	Neg	69
AITP14	49	NT	NT	Neg	Pos	54, 83
AITP15	60	11/13	03/06	Pos	Neg	70*
AITP16	104	11/15	06/06	Pos	Pos	3, 47, 68, 74, 77, 82
AITP17	163	01/03	02/05	Neg	wPos	None
AITP18	62	13/13	03/06	Pos	NT	2, 44, 53, 82
AITP19	152	15/15	06/06	Pos	Pos	2, 47, 48, 52, 82*
AITP20	61	04/15	03/06	Pos	Pos	2, 47, 50, 53, 70, 82*
AITP21	7	0103/15	05/06	Pos	Pos	1, 2, 29, 34, 44, 47, 49, 81, 82
AITP22	76	15/15	06/06	Neg	Pos	2, 47, 53, 77, 82*
AITP23	5	07/15	02/06	Pos	Pos	5, 30, 31, 36, 47*, 54, 60, 61, 86
AITP24	163	01/07	03/03	Pos	wPos	2, 3, 44, 47, 53, 56, 70, 82
AITP25	76	NT	NT	Pos	Neg	82*
AITP26	NT	NT	NT	Neg	Pos	2, 47, 53*, 62, 63
AITP27	95	NT	NT	Pos	Neg	None
AITP28	260	NT	NT	Pos	Neg	4, 7, 9, 11, 21, 23, 24, 43, 57, 63, 69, 70*
AITP29	217	NT	NT	Pos	Pos	5, 9, 17, 32, 33, 36, 38, 40, 52, 53, 57, 70
AITP30	121	NT	NT	Neg	Neg	2, 20, 41, 44, 47, 53, 76
AITP31	327	NT	NT	Pos	Neg	2, 37, 47, 65, 82*

Patient with AITP	Platelet count at testing, × 10⁹/L	HLA-DR type DRB1*	HLA-DQ type DQB1*	Anti-GPIIb/IIIa status		Stimulatory peptides, SI > 3
Patient with AITP	Platelet count at testing, × 10⁹/L	HLA-DR type DRB1*	HLA-DQ type DQB1*	Serum	Eluate	Stimulatory peptides, SI > 3
AITP1	10	03/11	02/03	Pos	wPos	2, 3, 44, 53, 68, 81, 82
AITP2	102	07/11	02/03	Pos	wPos	42, 49, 50, 58, 60, 67, 70, 71, 72, 73, 74, 77, 78, 80, 81
AITP3	3	01/01	05/05	Pos	Pos	2, 44, 50, 80, 82*
AITP4	14	01/04	03/05	Neg	NT	72, 82*
AITP5	163	03/04	02/03	Neg	Pos	82*
AITP6	33	03/07	02/03	Neg	NT	None
AITP7	3	03/03	02/02	Pos	Pos	8, 11, 14, 15, 35, 40, 47, 56, 70, 82*
AITP8	16	03/07	02/02	Neg	NT	29, 34, 35, 36, 40, 44, 5, 77*, 78, 80, 81
AITP9	338	15/15	06/06	Neg	Pos	2, 6, 7, 14, 15, 30, 46, 47, 53, 82
AITP10	394	01/03	02/05	Pos	wPos	2, 3, 44, 47, 53, 82*
AITP11	177	04/13	03/06	Pos	Pos	2, 32, 47, 53, 77, 82*, 86
AITP12	170	03/04	02/03	Pos	Pos	9, 17, 31, 53, 81, 82
AITP13	127	NT	NT	Pos	Neg	69
AITP14	49	NT	NT	Neg	Pos	54, 83
AITP15	60	11/13	03/06	Pos	Neg	70*
AITP16	104	11/15	06/06	Pos	Pos	3, 47, 68, 74, 77, 82
AITP17	163	01/03	02/05	Neg	wPos	None
AITP18	62	13/13	03/06	Pos	NT	2, 44, 53, 82
AITP19	152	15/15	06/06	Pos	Pos	2, 47, 48, 52, 82*
AITP20	61	04/15	03/06	Pos	Pos	2, 47, 50, 53, 70, 82*
AITP21	7	0103/15	05/06	Pos	Pos	1, 2, 29, 34, 44, 47, 49, 81, 82
AITP22	76	15/15	06/06	Neg	Pos	2, 47, 53, 77, 82*
AITP23	5	07/15	02/06	Pos	Pos	5, 30, 31, 36, 47*, 54, 60, 61, 86
AITP24	163	01/07	03/03	Pos	wPos	2, 3, 44, 47, 53, 56, 70, 82
AITP25	76	NT	NT	Pos	Neg	82*
AITP26	NT	NT	NT	Neg	Pos	2, 47, 53*, 62, 63
AITP27	95	NT	NT	Pos	Neg	None
AITP28	260	NT	NT	Pos	Neg	4, 7, 9, 11, 21, 23, 24, 43, 57, 63, 69, 70*
AITP29	217	NT	NT	Pos	Pos	5, 9, 17, 32, 33, 36, 38, 40, 52, 53, 57, 70
AITP30	121	NT	NT	Neg	Neg	2, 20, 41, 44, 47, 53, 76
AITP31	327	NT	NT	Pos	Neg	2, 37, 47, 65, 82*

NT indicates not tested; Pos, positive reaction; wPos, weak positive reaction; Neg, negative reaction; SI, stimulation index.

Immunodominant peptides.

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