Table 2

Immunoglobulin evaluations in children more than 2 years after transplantation (n = 21)

Normal for age n*Low, nHigh, n
IgG levels for infants off IVIG 13 
IgA levels 15 
IgM levels 17 
IgE levels 15 
Normal for age n*Low, nHigh, n
IgG levels for infants off IVIG 13 
IgA levels 15 
IgM levels 17 
IgE levels 15 

All values listed were obtained at least 1 year from transplantation and most are within 1 year of the present time. Eighteen infants were off IVIG. Of the 3 on IVIG, two subjects have not been taken off IVIG and have not been tested for antibody formation by the local physician. The patient with ectodermal dysplasia remains on IVIG because this patient does not have T-cell proliferative responses to tetanus toxoid.

*

The years after transplantation are used instead of years of life for the Ig levels. Thus, normal values in mg/dL are as follows: IgA, 15 to 108 for 2 to 3 years, 21 to 144 for 4 to 5 years, 22 to 141 for 6 years, 38 to 240 for 7 years, 32 to 248 for 8 to 10 years, and 40 to 277 for 11 to 12 years; IgM is 43 to 202 for 2 to 3 years, 31 to 163 for 4 to 5 years, 43 to 177 for 6 years, 37 to 151 for 7 years, 42 to 185 for 8 to 10 years, and 42 to 174 for 11 to 12 years. The normal values for IgE in IU/mL are as follows: 0-126 for 2 years, 3-135 for 3 years, 1-219 for 4 years, 2-158 for 5-7 years, 2-524 for 7-10 years, and 4-437 for 10-15 years. Note: “low” is below these levels and “high” is above these levels.

IgG levels are not included for 6 patients. This includes the 3 patients on IVIG. Three others have not had IgG levels obtained since stopping IVIG.

Not done after year 1 in one patient.

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